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Archive for 2017|Yearly archive page

Magnolia, Cancer’s Worst Enemy

In Alternative Cancer Therapies, Breast Cancer, Cancer, colon cancer, Uncategorized on December 8, 2017 at 7:43 am

While many people have taken magnolia to reduce stress-related symptoms such as anxiety, insomnia, and depression, the health benefits of magnolia go well beyond that. Importantly, magnolia can be used to help detoxify the body, soothe the digestive system, and to help prevent and treat cancer.

The hearty nature of magnolia shrubs and trees on which the beautiful magnolia flower grows has allowed them to offer a powerful organic nutrient with amazing health benefits. These virtues are recognized by modern medicine, Chinese Traditional medicine, and herbalists worldwide.  This bioactive natural product is known as honokiol.

Recent studies have demonstrated anti-inflammatory, anti-angiogenic, apoptotic, anti-oxidative, and overall anti-cancer properties of honokiol in vitro and in preclinical models. Honokiol targets multiple signaling pathways including nuclear factor kappa B (NF-κB) signal transducers and activator of transcription 3 (STAT3), epidermal growth factor receptor (EGFR), and mammalian target of rapamycin (m-TOR), which have great relevance during cancer initiation and progression.

Honokiol also shuts down the leptin signaling network, which is significant for obese patients. Leptin-induced tumors quickly learn to evade all the usual biological checkpoints that keep tumors from growing and spreading.  Once the leptin helps the tumor achieve this state, the tumor is poised to migrate and morph from a non-invasive tumor to an invasive tumor. Research done at Johns Hopkins found that honokiol is able to suppress some of the proteins in the leptin network.

The link between obesity, leptin, and breast cancer is well known, yet this hasn’t changed how breast cancer patients are diagnosed or treated, nor do doctors check patients for leptin or leptin receptor levels. Some studies suggest that breast cancer cells that have been exposed to high levels of leptin over several years might also be less sensitive to the chemo drug tamoxifen, rendering it, well,  less effective (just one more reason why traditional remedies are not always the best solution).

Hopefully more doctors will discover this natural remedy soon, but in the meantime, you are empowered to take advantage of magnolia’s offerings. The immense chemo-preventive (anticancer) capabilities of magnolia cannot be overlooked.

Anticancer Benefits of Magnolia:

  • stimulates the lymphatic system and increases the level of toxins being eliminated from the body
  • inhibits angiogenesis (the development of new blood vessels tumors require to survive)
  • powerful antioxidant
  • promotes apoptosis (cancer cell death)
  • down-regulates cancer-promoting genes
  • inhibits the growth of Helicobacter pylori, known to significantly increase the risk for gastric cancers
  • able to cross the blood-brain-barrier and inhibit brain tumor growth[i]
  • increases sensitivity to radiation -induced cytotoxicity in lung and other cancers
  • shuts down the leptin signaling network

While studies have found honokiol to be effective in gastrointestinal, breast, head and neck, prostate, ovarian, lung, skin, brain, and many other cancers, here are just a few specifics of this powerful magnolia:[ii]

  • inhibits the growth in breast cancer cell lines (MDA-MB-231, SK-BR-3, MDA-MB-436, ZR-75-1and T47-D, MCF-7, 4T1) in a dose dependent manner regardless of their HR, HER2 or p53 status
  • is effective against estrogen-receptor positive as well as estrogen-receptor negative breast cancers
  • induces apoptosis in human prostate cancer cells irrespective of their androgen responsiveness or p53 status, and significantly decreases PSA counts
  • exhibits growth-inhibitory effects against two human pancreatic cancer cell lines (MiaPaCa and Panc1)
  • effective in leukemia cell lines viz. B-CLL and Molt 4B
  • induces apoptosis in human multiple myeloma cell lines including dexamethasone-sensitive (MM.1S) and dexamethasone-resistant (MM.1R, RPMI-8226, U266 and SU-DHL-4) cells and in tumor cells
  • significantly inhibits the invasion and colony formation of highly metastatic renal cell cancers cells 786-0 in a dose-dependent manner[iii]

How to Take Magnolia:

The bark, cones and leaves of the magnolia tree can be cooked and boiled down to a syrupy extract. Given that many of us do not have a field of magnolia in our back yards, a supplement may be best.

Small doses (30 mg) may be effective for anxiety and depression.  Slightly more might be helpful for those dealing with intense stress or insomnia. My oncologist used to call it “herbal Valium—all the relief without the wobbly knees”. He recommended it for sleep and stress relief as well as for cancer. The brand I take, NutriCology comes in capsule form, 200mg. The suggested dose is one daily, before bed. For smaller doses, you can buy it in powder formHonoPure is another excellent product that comes highly recommended.

The suggested dosage for cancer averages between 200 and 800 mg, up to three times a day (but limit to one dose before bed if drowsiness will be an issue and high doses only under the guidance of a medical doctor).

Magnolia should not be taken by pregnant women or at very high doses as it may cause headaches, dizziness, and vertigo. Keep magnolia away from infants and animals. Magnolia may cause a sedative effect and can interact with alcohol. Operating dangerous equipment or driving while taking magnolia extract is not recommended. For best results, take before bed.

This information is for educational purposes only and is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist and make your own decisions.  The information provided is from my research and not to be taken as scientific evidence. 

As an Amazon Affiliate, we may earn a small commission for the sale of products purchased from this site. These small commissions help to pay for the maintenance of this site as well as for the time spent researching and writing on topics relevant to your optimal health, but are achieved at no additional cost to  you.

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a breast cancer survivor and certified holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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REFERENCES:

https://www.realnatural.org/magnolia-bark-extract-treats-multiple-invasive-cancers/

https://www.sciencedaily.com/releases/2008/07/080711214125.htm

 

https://www.spandidos-publications.com/ijo/46/6/2293

https://hub.jhu.edu/2016/07/06/magnolia-honokiol-breast-cancer-obesity/

[i] /www.ncbi.nlm.nih.gov/pmc/articles/PMC3663139/

[ii] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663139/

[iii] https://www.spandidos-publications.com/ijo/46/6/2293

Recommended Cookbooks for Cancer Patients

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Anticancer foods, foods for colon cancer, foods for breast cancer, Books for Cancer Patients, Breast Cancer, Uncategorized on November 29, 2017 at 9:53 am

With the holidays soon upon us, you may be looking for the perfect gift for a loved one with cancer. Clients ask me all of the time, what can I eat? What should I eat? Or they lament that healthy eating doesn’t taste good.  Well, here are a few fantastic books that will be sure to dazzle taste buds and inspire trips to the kitchen.

books-1-e1511966525908.jpg

Some of My Favorites:

The Oh She Glows Cookbook: Over 100 Vegan Recipes to Glow from the Inside Out  

Nutrition Stripped: 100 Whole-Food Recipes Made Deliciously Simple 

Whole World Vegetarian 

Medical Medium Life-Changing Foods: Save Yourself and the Ones You Love with the Hidden Healing Powers of Fruits & Vegetablesbooks 2

Eat Drink Shine: Inspiration from Our Kitchen: Gluten-free and Paleo-friendly Recipes by the Blissful Sisters 

Plenty: Vibrant Vegetable Recipes from London’s Ottolenghi

Eating Well Through Cancer: Easy Recipes & Tips to Guide you Through Treatment and Cancer Prevention 3rd Edition

Here’s a new book that might be the perfect gift for one who is short on time, but craves healthy meals.  The Healing Slow Cooker: Lower Stress * Improve Gut Health * Decrease Inflammation

Elyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and certified holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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Why Aromatase Inhibitors Fail Women

In Alternative Cancer Therapies, Alternatives to Anti-Hormone Therapy For Breast Cancer, Alternatives to Hormone Therapy for Breast Cancer, Alternatives to Tamoxifen, Breast Cancer, Tamoxifen, Uncategorized on November 13, 2017 at 5:27 am

Aromatase inhibitors fail when tumors outsmart them.  Researchers have long been studying how resistance to aromatase inhibitors (AIs) happens so that they can find a solution. The resistance effectively makes these drugs powerless, causing the cancer to return. One in every four or five women relapse within ten years of AI treatment and develop metastatic cancer. [i]

Estrogen plays an important role in the development of hormone-dependent breast carcinomas, or at least some estrogens do. While ovarian estrogen synthesis ceases at menopause, peripheral and local tissue’s aromatization of androgens to estrogens continues and becomes the main source of estradiol (the more cancer-promoting estrogen). What this means is that while your ovaries are no longer producing estrogen after menopause, and your adrenals are producing only a small amount, breast cancer cells may actually have a way to produce their own food supply.

Theoretically, the aromatase inhibitor could be reducing circulating estrogen to dangerously low levels, while estrogen in the breast, axillary, and belly could still be dangerously high. Hence, AIs fail the patient, who then suffers the ill-effects of the drugs with no benefit.

The Research

Until recently, scientists assumed the tumors developed resistance in some way, but didn’t know how. Scientists have now discovered why AIs may stop working in some patients. Research done at the Imperial College London and the European Institute of Oncology in Milan has found that some breast tumors evolve to make their own estrogen, rendering AIs ineffective. While the ovaries cease to produce estrogen after menopause, the hormone is still made in other tissues via the enzyme aromatase.[ii] The team, led by Dr Luca Magnani, found that in one in four patients taking AIs, the tumors had increased production of aromatase in the cancer cells. They found that the tumors were able to increase the number of aromatase genes via a process known as amplification.

So, while AIs work by cutting off the tumor’s fuel supply (estrogen), the cancer adapts by making its own –an efficient survival mechanism. The research points to a particular gene (CYP19A1).  When more copies of this gene are produced, it triggers the increased production of aromatase, the very enzyme the drugs are trying to block. This allows cancer cells to make their own estrogen and thus reproduce and spread.[iii] It seems to be a bit of a survival mechanism-the AI cuts off the food supply so the tumor outsmarts it by making its own.

We found that 21.5% of AI-treated, relapsed patients had acquired CYP19A1 (encoding aromatase) amplification (CYP19A1amp)…CYP19A1 amplification caused increased aromatase activity and estrogen-independent ERα binding to target genes, resulting in CYP19A1amp cells showing decreased sensitivity to AI treatment. These data suggest that AI treatment itself selects for acquired CYP19A1amp and promotes local autocrine estrogen signaling in AI-resistant metastatic patients.[iv]

When an aromatase inhibitor stops working, most oncologists will try another type of AI.  The problem is that if the cancer cells have started making their own aromatase, the second (or third) drug will be useless. Identifying the over-expression of the CYP19A1 may help doctors determine which women are not good candidates for AI therapy or who might be candidates for alternative therapies. The aforementioned researchers are now working on a test to identify whether a patient’s tumor has started to increase aromatase production, and make its own estrogen.

Dr. Magnani also suggested that when cancer returns, a biopsy should be done to see how the cancer has evolved, which may help guide treatment decisions. Often this can be helpful, but just as often, it fails to offer much information. This is a decision you need to make in consultation with your oncologist or other qualified professional.

Obesity Plays a Role

Excess body weight has been linked to an increased risk of postmenopausal breast cancer, and research also suggests that obesity is associated with poor prognosis in women diagnosed with early-stage breast cancer. Fat tissue contains the enzyme aromatase that converts hormones called androgens to estrogens. Human abdominal, breast, and axillary fat have the ability to convert androgens into estrogens.

So, heavier women end up with higher blood estrogen levels as well as enhanced local production of estrogen than leaner women. Elevated serum estrogen levels as well as enhanced local production of estrogen have been considered primary mediators of how increased body weight promotes breast cancer development in postmenopausal women.

On the Horizon

I have long been pointing out that most of have seriously declining levels of estrogen as we age –which has been found to compromise overall health. For this reason, AIs are quite dangerous as they block essential estrogen.

However, it has recently been reported that plasma estrogen levels do not necessarily reflect tissue estrogen concentrations. Several studies have found that tissue estrogen levels may be ten- to 20-fold higher compared to plasma levels in postmenopausal women. Furthermore, recent studies have demonstrated that a large proportion (close to 100%) of the biologically active estrogen is considered to be produced locally in the breast carcinoma after menopause.[v] Therefore, likely a more effective method would be to inhibit estrogen of breast tissue than that of systemic circulation. More studies need to be done on this.

At this point, studies are being conducted in China to see if a locally-applied aromatase-inhibiting patch using letrozole would be effective and offer a less toxic solution to the standard drug AIs.

As reported in AAPS PharmSCiTech (a Journal of the American Association of Pharmaceutical Scientists), a mouse study revealed that compared with oral administration, transdermal administration could produce high local drug concentrations and low circulating drug concentrations. This could reduce systemic side effects. Therefore, it might be a new option for breast cancer therapy to inhibit aromatase activity via transdermal patches for site-specific delivery of letrozole.

But again, more studies need to be done to determine if a local patch would be effective for cells outside the breast area, and independent studies should also be done (ones not paid for by a pharmaceutical company).

So, should women with estrogen receptor-positive breast cancer take inhibitors of estrogens? The decision of whether or not to use estrogen blockers is a complex one that each woman can only make if fully informed. The potential negative effects on the brain, heart, and overall quality and quantity of life, as well as treatment failure, should be weighed against the immediate risk of recurrence.

However, in making a treatment decision, it is most important to speak with an oncologist who is fully aware of the limitations and potential negative effects of these drugs and who is prepared to discuss alternative options. It is equally important to educate yourself on natural alternatives as typically these options are not discussed by medical doctors.

Important is to realize that in the presence of adequate progesterone, estrogen cannot easily fuel breast cancer tumors.[vi] Perhaps for now, a better solution is to make every effort to reduce aromatase activity and to increase production of progesterone.

Progesterone may also be the answer to why AIs seem to work for some.  I could postulate that the answer again might be progesterone, especially for those patients who are PR + as well as ER+, but that is just one possibility.

For more information regarding consideration of natural alternatives, please read:

Natural Alternatives to Hormone Therapy for Breast Cancer  

Why You May Want to Reconsider Estrogen-Blocking Aromatase Inhibitors and Tamoxifen 

* The CYP19A1 gene provides instructions for making an enzyme called aromatase. This enzyme converts a class of hormones called androgens, which are involved in male sexual development, to different forms of the female sex hormone estrogen. Mutations in this gene can result in either increased or decreased aromatase activity.

This information is for educational purposes only and is not a recommendation to forgo anti-hormone therapy. It is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist and make your own decisions.  The information provided is from my research and not to be taken as scientific evidence. 

ej portrait 150resElyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and certified holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

Follow Elyn on Facebook

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[i] https://www.nature.com/articles/ng.3773   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326683/

[ii]

http://www3.imperial.ac.uk/newsandeventspggrp/imperialcollege/newssummary/news_23-1-2017-16-57-16

[iii] https://www.ncbi.nlm.nih.gov/pubmedhealth/behindtheheadlines/news/2017-01-24-new-insights-into-why-breast-cancer-drugs-fail-for-some-women/

[iv] https://www.nature.com/articles/ng.3773

[v] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974128/

[vi]  http://ajcn.nutrition.org/content/45/1/277.short

 

Why You May Want to Reconsider Estrogen-Blocking Aromatase Inhibitors and Tamoxifen

In Alternatives to Anti-Hormone Therapy For Breast Cancer, Alternatives to Tamoxifen, Breast Cancer, Natural Alternatives to Aromatase Inhibitors, Uncategorized on November 7, 2017 at 9:50 am

The current oncological recommendations for anti-hormone therapy (endocrine therapy) for postmenopausal women with early-stage breast cancer vary. Some oncologists recommend aromatase inhibitors for five years, with tamoxifen to follow and some the reverse, and some just one or the other. However, the recommendations rarely take into consideration risk of prior cardiovascular disease history, cardiovascular disease risk, or overall risk of death when choosing between the different therapeutic options. (For premenopausal women, the standard is usually tamoxifen, with little attention to risk factors for blood clots, stroke, and endometrial cancer.)  Importantly, while both therapies can prolong disease-free survival, they don’t necessarily increase overall survival.

In the discussion of adjuvant endocrine therapy, doctors downplay the fact that aromatase inhibitors (AIs) are associated with musculoskeletal symptoms, heart damage, osteoporosis, and increased risk of bone fracture. Estrogen protects against heart disease, and consistent research has suggested that the suppression of estrogen raises the risk of cardiovascular disease, among other life-challenging issues. AI treatment reduces nearly all circulating estrogen. Estrogen is essential to the health of all parts of your body, from your eyes to your heart to your brain to everywhere else.

Many doctors also fail to stress that tamoxifen is associated with an increased risk of uterine cancer, stroke, deep venous thrombosis (blood clots), and severe muscle pain. They also fail to inform their patients that while both therapies can prolong disease-free survival, they rarely increase overall survival—especially in the case of aromatase inhibitors. All this at a tremendous cost to quality of life.

Tamoxifen and aromatase inhibitors have distinct toxicity profiles. However, individual studies have not shown a significant difference in overall toxicity between patients treated with these therapies. The lack of association between disease-free survival and overall survival prompted a 2011 meta-analysis published in the Journal of the National Cancer Institute. The study evaluated the toxicities of the two endocrine therapy options.

The Research:

The meta-analysis confirmed that an aromatase inhibitor (AI) may not the best therapy for all postmenopausal women with hormone-receptor positive, early-stage, breast cancer. The authors conducted the study to clarify why AIs, when compared with tamoxifen, increased disease-free survival but not overall survival. AI toxicities were suspected to counteract decreased recurrence rates.[i] However, as presented in the analysis, tamoxifen wasn’t necessarily safer than AIs, so the authors concluded that switching from tamoxifen to AIs would  balance the efficacy and toxicity of these treatments. What this means to you is that they are recommending that you ‘switch’ from one drug to another after a few years to reduce toxicity–but that also means you suffer the consequences of both drugs.

The authors noted that although several large randomized trials have examined the benefit of the aromatase inhibitors anastrozole, letrozole, and exemestane — as compared with 5 years of tamoxifen — the trials have failed to demonstrate a statistically significant improvement in overall survival.

The Methods:

Relevant trials were identified through a search of the MEDLINE and EMBASE databases, a search of the American Society of Oncology Annual Meetings from 2000 through 2009, and a search of the San Antonio Breast Cancer Symposium Annual Meetings from 2000 through 2009. 377 relevant articles were identified, of which 7 randomized controlled phase-3 trials with 30,023 patients met inclusion criteria.

The analysis considered six adverse events: cardiovascular disease, cerebrovascular disease, venous thrombosis (DVT), bone fracture, endometrial cancer, and other secondary cancers.

The Highlights: (Noting that longer duration of one therapy implies a shorter duration of the other)

  • Longer duration of AI use was associated with higher odds of developing cardiovascular disease.
  • Longer duration of AIs was associated with a 66% reduction in the odds of developing endometrial cancer compared with tamoxifen use.
  • Both AIs and tamoxifen increase the risk of other second cancers, but switching from tamoxifen to aromatase inhibitors may decrease the odds of second cancers.
  • Longer durations of aromatase inhibitor use were associated with decreased odds of venous thrombosis compared with tamoxifen.
  • Longer durations of AIs were associated with increased odds of bone fractures compared with tamoxifen.
  • Longer durations of AI use was associated with a statistically significant increase in the risk of raised cholesterol (hypercholesterolemia. Shorter durations of AIs might reduce the odds of high cholesterol.
  • The relative harm of 2 to 3 years of tamoxifen was not reduced by switching to aromatase inhibitors.
  • Compared with those treated with 5 years of either tamoxifen or aromatase inhibitors, those treated with a switching strategy had a statistically lower risk of death without breast cancer recurrence.
  • A retrospective cohort study of women diagnosed with breast cancer at age 66 or older between 1992 and 2000 found that more patients died of cardiovascular disease than of breast cancer.[ii] The researchers recommended that the age of the patient be taken into consideration when choosing between endocrine therapies (or in this author’s opinion, instead offering holistic alternatives).

While the study was performed to compare the two conventional treatment options, sadly they did not simultaneously compare the effectiveness of natural alternatives. Again, use of aromatase inhibitors vs tamoxifen is associated with increased risk for cardiovascular disease, cholesterol, severe muscle and joint aches, and bone fractures. Use of tamoxifen vs aromatase inhibitors is associated with increased risk for venous thrombosis, stroke, and endometrial cancer. Clearly both of these toxic therapies cause harm, often more harm than good — even if one does switch from one therapy to the other.

Other Reasons for Opting Out in Favor of Natural Alternatives:

  • A study published in the Journal of Clinical Oncology, 2016, reported that women in their 40’s with chemotherapy-induced amenorrhea should avoid aromatase inhibitors. Many women who have ceased menstruating post-chemo later recover ovarian function. What the researchers found was that ovarian estrogen production will decrease the effectiveness of AI therapy and that the therapy could actually stimulate ovarian production of estrogen. Unfortunately, the researchers concluded that the way to prevent this would be to shut down ovarian function as well as to offer tamoxifen.  [iii]
  • A study reported at the San Antonio Breast Cancer Symposium in 2106 reported that endothelial dysfunction, a predictor of cardiac disease, is a significant side effect of AI therapy among postmenopausal women, posing the problem again — that while the therapy may inhibit recurrence, it does not improve overall survival time.[iv] Estradiol appears to be important for regulating healthy endothelial function.
  • Endogenous estrogen (the estrogen your body produces) is neuroprotective. The breadth of literature on the role of estrogen in cognitive function is vast. Many women will attest to the fact that peak cognitive function corresponds with cyclic changes in circulating estrogen during their menstrual cycle.
  • Estrogen has also been found to suppress the inflammatory processes that contribute to neurodegeneration as well as to improve stroke outcome.[v] It is well documented that women are ‘protected’ against stroke until menopause, when estrogen levels decline.
  • Numerous studies have shown that beyond the aforementioned complications, tamoxifen can increase the risk of developing liver cancer and raises overall inflammation of the body, a known precursor to cancer.
  • A study reported at the San Antonino Breast Cancer Symposium 2016 looked at endothelial dysfunction, a predictor of cardiac disease.  Interestingly, they determined that the vast majority of participants who had increased cardiac risk after taking AI therapy would not have been considered at risk pre-treatment. The study indicated that the cancer benefit may not be worth the cardiac risk, both for younger and older patients.
  • Also reported at the 2016 Symposium was that AIs, associated with reductions in endothelial function, could contribute to cardiovascular disease independent of the duration of therapy.

With a growing number of cancer survivors, it is very important that we look to understand the long-term complications of conventional cancer treatment. Most postmenopausal women with early-stage breast cancer are at greater risk of dying from cardiovascular disease than their breast cancer. Further, they are at greater risk of a significant reduction in quality and quantity of life from the other overwhelming effects of conventional treatments in general.  Even worse, most doctors don’t even bother to run hormone level tests–they simply prescribe the harmful drugs. Clearly, the current toxic anti-hormonal therapies cause harm, often more harm than good. The question to be asked is ‘is it worth it?”

But, my doctor says they work:

Research published in 2106 in the Journal of Clinical Oncology analyzed the information collected for the BIG 1-98 study that was designed to see whether AIs or tamoxifen was most effective. The study was rather useless—all it managed to say was that the treatments were so toxic that most women were either non-compliant or discontinued treatment due to the side effects. Sure can’t blame them. Again, while these treatments can prolong disease-free survival, they do not always prolong overall survival. This study made no mention of those who died without recurrence (meaning from treatment-induced effects). [vi] It also made no mention of safer alternatives, and likely instilled more unnecessary fear-based compliance out of those who read the study.

If your reason for reading this article was your desire for natural alternatives to anti-hormone therapy, please readNatural Alternatives to Hormone Therapy for Breast Cancer.

This information is for educational purposes only and is not a recommendation to forgo anti-hormone therapy. It is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist and make your own decisions.  The information provided is from my research and not to be taken as scientific evidence. 

ej portrait 150resElyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

Follow Elyn on Facebook

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[i] https://www.medscape.com/viewarticle/756567

[ii] https://www.ncbi.nlm.nih.gov/pubmed/21689398?dopt=Abstract&holding=f1000,f1000m,isrctn ; https://www.ncbi.nlm.nih.gov/pubmed/16944964

[iii] http://ascopubs.org/doi/abs/10.1200/JCO.2015.62.2985?rss=1

[iv] http://www.pnas.org/content/108/47/18879

[v] https://www.ncbi.nlm.nih.gov/pubmed/9445346

http://www.pnas.org/content/108/47/18879.full.pdf

[vi] http://ascopubs.org/doi/abs/10.1200/JCO.2015.63.8619

http://www.mdedge.com/oncologypractice/article/119926/breast-cancer/aromatase-inhibitor-effect-endothelial-function-may

 

 

 

 

Bone Broth: Elixir to Health

In Anticancer foods, foods for colon cancer, foods for breast cancer, Bone Health Cancer Treatments, Breast Cancer, Cancer, Uncategorized on November 6, 2017 at 2:53 pm

broth mastersThere are so many health benefits to bone broth. It is loaded with calcium, protein, potassium, collagen, and amino acids. But the benefits go beyond this.  Bone broth has been found to reduce inflammation as it is high in sulfated glycosaminoglycans (GAG’s) and glucosamine and chondroitin sulfate, which numerous studies have found help reduce inflammation (and pain) in the body.

All said, bone broth is powerful nutrition for anyone struggling with the side effects of conventional cancer treatment. Soothing to the throat and nourishing to the body.

The gelatin in bone broth supports healthy digestion. Importantly, bone broth helps repair the lining of your gut, which is something we hear about all of the time now.  Gut health=overall health. Leaky gut is the root cause of autoimmune disorders and many cancers.

You can make your own bone broth quite easily. Simply put the desired bones (chicken, beef, or a combination of both) into a pot; add some apple cider vinegar and let sit for about an hour. Add water to cover the bones, add a bunch of chopped vegetables and Celtic sea salt and boil. (You can google a plethora of recipes).  The problem for most of us is that you have to simmer this concoction for 24-72 hours, which can be an issue.

Hence, most of us resort to store-bought versions, which lack nutrients and taste. Some are down-right unhealthy, containing pesticides, fungicides, fluoride, and more.

This weekend I attended a wellness conference geared towards optimal health for all. I was gifted the opportunity to taste the best bone broth ever.  So, if you don’t have the time or desire to make your own, please know that Broth Masters broth is amazing. The combination of chicken and beef bones combined with the vegetables boosts the flavor.

I am not a fan of selling anything, but these folks are lovely—health conscious right down to the bone (pun intended).  However, right now if you use the code BROTH4LIFE you can receive $10 off your first order and if you buy a 20-pack, you get free shipping. Bon Appetit.

brothmasters photoOrder Broth Masters HERE.

Ingredients: Filtered water, grass fed beef bones, free range chicken bones, organic onions, organic carrots, organic celery, garlic, lemon juice, organic parsley and bay leaves.

Nutrition: (per cup, according to Broth Master independent studies)

  • 30% of your daily calcium requirement
  • 14 grams protein and only 80 calories
  • 290 mg potassium
  • 150 mg of sodium

 

Elyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

 Follow Elyn on LinkedIn

 

Cauliflower Black Beluga Lentil Stew

In Anticancer foods, foods for colon cancer, foods for breast cancer, Breast Cancer, Cancer, Uncategorized on November 5, 2017 at 6:58 pm

This cauliflower-black lentil stew is so delicious — please try it as it is loaded with health-promoting ingredients. It is so versatile. Today I did not have sweet potatoes or spinach on hand so I used carrots and watercress–but I did have both white and purple cauliflower, which was amazing. Other times I used the sweet potatoes and spinach. Always delicious.

cauliflower black lentilCauliflower-Black Lentil Stew:

Ingredients:

1 tablespoon coconut oil or ghee

1 large onion, diced, or 4 shallots, sliced

1 tablespoon minced fresh ginger, or 1 tsp dried

1-2 tablespoons curry powder or turmeric, to taste

1 ½ teaspoons ground coriander

¼ teaspoon cayenne pepper (optional)

1 1/2 teaspoon ground cumin

1 teaspoon Ceylon cinnamon

½ teaspoon ground cardamom

4 cups chicken bone broth or vegetable stock

1 cup black beluga lentils (red lentils may be substituted)

1 head cauliflower, cut into bite-sized florets

1 medium sweet potato, diced but not peeled (optional)

3 large carrots, sliced but not peeled,  3/4 inch thick (optional, but best to include either carrot or sweet potato or both)

3 stalks celery, sliced 1/4 inch thick (optional, but provides valuable anti-cancer apigenin)

1 cup baby spinach, arugula, or other green leafy vegetable, chopped if large leaves

1 teaspoon fine-grain Celtic sea salt (or Real Salt)

Freshly ground black pepper

1/2 cup chopped cilantro

1 avocado, optional, skin and seed removed, diced, or 1 tsp olive oil

Serves 4

Serve with Super Seed Bread or Flax Seed Muffins

  1. In a large saucepan, heat the coconut oil or ghee over low heat. Add the onion and sauté for 6-7 minutes until translucent. Add the garlic and sauté 1 more minute
  2. Stir in the spices and sauté for 2 more minutes
  3. Add the broth and lentils and stir to combine. Bring to a low boil, then reduce heat and simmer for 4-5 minutes
  4. Add the cauliflower, sweet potato and/or carrot, and celery. Cover and cook over low heat for 20-25 minutes, until the vegetables are tender. Season with salt and pepper
  5. Add the greens of choice and cook 3-5 minutes more, depending on the toughness of the greens
  6. Stir in cilantro; divide into 4 bowls
  7. Drizzle with olive or or top with diced avocado, if desired (the healthy fat will boost absorption of nutrients)

 

Why You Should Eat This: (beyond tempting your taste buds):

Cauliflower contains a variety of antioxidants that protect and repair DNA. It also exhibits strong anti-inflammatory activity that help detoxify the body of harmful toxins.

Onions and shallots have many anticancer benefits, offering potent antioxidant and anti-proliferation apoptotic abilities.

Garlic protects organs from heavy metal toxicity and contains the anticancer powerhouse B6.

Carrots reduce cancer growth and lower inflammation

Celery is rich in apigenin, which induces apoptosis through the p53 pathway

Sweet potatoes have many anticancer properties that dramatically lower one’s risk for breast and other cancers.

Ceylon cinnamon has cytotoxic properties (toxic to cancer cells) and helps regulate blood sugar

Curcumin (turmeric) is a powerful anti-inflammatory, anticancer spice that cuts off many pathways for cancer

Cumin is rich in antioxidants and is a natural immunity booster

Black beluga lentils are a rich source of plant protein and have high concentration of cancer-fighting anthocyanins

Spinach gives cancer the one-two punch. It protects DNA and inhibits cancer cell and tumor growth.

Cilantro is a strong detoxifier of heavy metals such a mercury

Avocado and olive oil offer significant anti-cancer, health-boosting nutrients

Elyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

Broccoli and Leaky Gut: Who Knew

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Anticancer foods, foods for colon cancer, foods for breast cancer, Breast Cancer, Cancer, colon cancer on October 30, 2017 at 4:19 pm

broccoli sprouts aIt is no revelation that cruciferous vegetables such as broccoli fight cancer in many ways.  Notably, broccoli contains a high amount of the cancer-busting and immune boosting substance sulforaphane. New research, however, shows that broccoli –and its cousins– actually heal leaky gut as well.

Leaky gut, or gut permeability, has risen to the forefront of medical concern as it has been found to be a source of many maladies, including cancer. This is because leaky gut blocks nutrient absorption and allows toxins from ingested foods to enter the blood stream. Dr Max Gerson had concern for this years ago, citing insufficient nutrition and overwhelming environmental toxicity to be the root cause of many dis-ease. Good gut-barrier function helps protect the intestines from toxins while allowing nutrients to be absorbed.

“There are a lot of reasons we want to explore helping with gastrointestinal health and one reason is if you have problems, like a leaky gut, and start to suffer inflammation, that may then lead to other conditions, like arthritis and heart disease,” said Perdew. “Keeping your gut healthy and making sure you have good barrier functions so you’re not getting this leaky effect would be really big.” Gary Perdew, the John T. and Paige S. Smith Professor in Agricultural Sciences, Penn State.

Recent research shows that gut health affects overall health, including systemic inflammation, heart disease, and cancer. Broccoli, and other cruciferous vegetables, appears to offer assistance.

AHR (Aryl hydrocarbon receptor) is found in many organs. It binds environmental toxins, detoxifying the carcinogenic effects. Cruciferous vegetables contain an organic chemical compound called indole glucosinolates, which breaks down in the stomach into substances known as indolocarbazole (ICZ).

In a recent study performed at Penn State University, it was found that ICZ  activates AHR. In doing so, it  boosts immune function and improves the balance of the microbiome in the human gut, enhancing host barrier function.[i]

How much do you need?  Well, a lot —  and every day.  Consider a good fist-full of broccoli sprouts, a cup of Brussels sprouts, or about 3 and half cups of broccoli per day (note that when sliced, you will yield more per cup of Brussels or broccoli, so you will need less).

Just remember that it is important to avoid things that irritate the gut lining; otherwise, it could be an uphill battle. Avoid alcohol, caffeine, coffee, chocolate, chemicals in foods, gluten, processed foods, antibiotics, NSAIDs,  as well as vinegar and other fermented foods (for some people).  Candida also contributes to leaky gut. Some people may also need to avoid grains. This is because grains can be difficult for the body to breakdown and digest, resulting in inflammation in the digestive tract.

 

So, What’s the Big Deal About Sulforaphane?

Sulforaphane, abundant in broccoli, is a sulfur-containing compound found in cruciferous vegetables. It supports matrix metalloproteinase-9 (MMP-9) activity which reduces the breakdown of connective tissue within a cell that impede the expansion of existing tumors. Matrix MMP-9 plays important roles in tumor invasion and angiogenesis. Secretion of MMP-9 has been reported in various cancer types including lung, colon, and breast cancer.

Sulforaphane also kills off cancer cells, including cancer stem cells, which is essential for combating cancer metastases. It also restrains certain pro-inflammatory compounds that are associated with chronic inflammation and cancer.

Sulforaphane also helps support the anti-inflammatory Nrf2 pathway which protects cells against oxidative and free radical activity. It supports the detoxification process by inducing Phase 2 detoxification enzymes, inhibiting the activation of pro-carcinogens, and by boosting cellular glutathione levels.  Sulforaphane promotes cancer cell death and inhibits cancer cell proliferation. It also supports the immune system and in particular, increases Natural Killer Cell activity.

This is just one more reason to enjoy cruciferous vegetables daily.  Cauliflower, watercress, kholrabi, and arugula are a few of the other amazing crucifers aside from broccoli.kholrabi

Just remember to lightly steam or cook crucifers.  Adding some organic grass-fed (pastured) butter or olive oil can help as well.  Avoid overcooking as this will destroy the health benefits.  If you prefer your veges to be, well, a bit more well-done, then chop them and allow to sit for 40 minutes before cooking. This allows the family of enzymes known as myrosinase to form. Myrosinase converts glucoraphanin to sulforaphane.  Without myrosinase, the body cannot absorb surlforaphane. It also helps to consume myrosinase-containing foods, such as mustard seed, with cruciferous veges as this will further maximize sulforphane availability.

A tasty side dish could include lightly cooked broccoli dressed with lemon-infused olive oil, black pepper, and some mustard seeds or powder. Freshness counts, so when possible, shop your local farmer’s market and cook your produce the same day (much of the value is lost after 5 days or so).

Curcera-SGS is an excellent supplement if you cannot find broccoli sprouts.

For more information on the benefits of cruciferous vegetables, please read my post Broccoli and Watercress Sprouts Fight Cancer.

Another good read is Eat Dirt: Why Leaky Gut May Be the Root Cause of Your Health Problems and 5 Surprising Steps to Cure It.

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

Follow Elyn on Facebook

 

[i] http://news.psu.edu/story/486322/2017/10/13/research/it-or-not-broccoli-may-be-good-gut

BPA: The Bathroom Toxin that Fuels Breast Cancer

In BPA and breast cancer, Breast Cancer, Inflammatory Breast Cancer on October 9, 2017 at 6:08 pm

Most people worry about the BPA (bisphenol A) in plastic water bottles, but did you know that this dangerous chemical is in your toilet paper? Even the ‘greenest’ toilet paper you find in your health food store is contaminated.

BPA is also found on cash register receipts, paper napkins and towels, copy paper, in dental fillings, and more.  Remember how years ago the registers at the grocery store would always jam? The addition of BPA made things go much smoother (and helped stabilize the ink), and that is the same for toilet paper and other paper products.

Why the fuss?  Studies show that BPA and other endocrine disrupting chemicals help promote the development of breast cancer tumors through the proliferation of estrogen receptor (ER)-positive human breast cancer cells. BPA mimics estrogen, and understanding the effects of it has helped scientists and researchers to understand how cell proliferation happens in an estrogen independent manner. In other words, once again I remind you that the estrogens your body makes cannot always be blamed for your cancer—but that is a whole other topic.  Chemical toxins must be acknowledged and addressed.

Importantly, for those who choose conventional treatments, BPA has been found to prevent chemotherapy drugs from inducing apoptosis (cancer cell death) in breast cancer cells — hence, rendering them rather ineffective.[i]

Furthermore, BPA appears to aid the survival of inflammatory breast cancer cells, the most lethal and fastest-growing form of breast cancer. A recent study performed by researchers at the Department of Surgery at Duke University School of Medicine and the Duke Cancer Institute found that BPA increases the cell signaling pathway MAPK (mitogen-activated protein kinases) in inflammatory breast cancer (IBC) cells. This offers valuable insight as to how the disease grows. Plus, the presence of BPA may actually lead to resistance to cancer drugs targeting this pathway, which helps explain why conventional medicine is so often ineffective against IBC. (See also the note on this below).

The researchers also found that BPA inhibits the efforts of cancer drugs that normally work to kill IBC cancer cells by inhibiting EGFR signaling. They determined that when the cells were tainted with BPA, EGFR (epidermal growth factor receptor) activation nearly doubled and signaling to the MAPK pathways also increased. The result was a rise in cancer cell growth.

Despite efforts to find a safer alternative to BPA, so far not so good. One substance, BPS (Bisphenol S) also acts like estrogen in breast cancer cells. A study done on the effects of BPS found that not only did BPS induce the proliferation of breast cancer cells, but may also cause breast cancer to be more aggressive.  That study also found that those who have the BRAC1 mutated gene and are exposed to BPS may have an even greater risk of developing breast cancer.

What can you do? Fortunately, BPA can be flushed out of the body in about a day or so—assuming you do not expose yourself in the meantime. BPA is metabolized rather quickly, but that doesn’t make it any less dangerous. Further, if you have impaired detoxification, say from the MTHFR or other mutation (or just an over-worked liver), you may not metabolize toxins as efficiently.  Here are a few tips for extracting and excreting BPA:

  • Consume probiotics, whether in supplement or fermented food form (kimchi, natural sauerkraut, etc.)
  • Drink black tea
  • Consider brisk exercise and saunas
  • Consume quercetin, found in apples, red grapes, tea, and onions, as well as in supplement form
  • Get adequate folate from foods or supplements (not folic acid, which is toxic)
  • Take royal jelly
  • Maximize melatonin (get to bed by ten or take a low-dose supplement)

Importantly, while curcumin does not necessarily flush BPA out, it does inhibit the proliferative effects of BPA on human breast cancer cells. Treatment with curcumin, a miR-19 inhibitor (miR-19 is  involved in BPA-mediated MCF-7 cell proliferation), leads to suppression of proliferation, growth, and invasion/metastasis of cancer cells. Sadly, most oncologists tell their patients not to take supplements, including curcumin, during treatment.

I also recommend overall detoxification strategies. If you would like a copy of my Estrogen and Detoxification Handouts, you can order them via my Contact Page.

So now that you are BPA free, how can you further avoid exposure?

Keep in mind that breast cancer rates have soared in the last 50 years.  Not coincidentally, the replacement of glass and cotton items with plastic and other chemical laden products has also soared—the connection is clear. Give a few of these suggestions a try:

  • Use glass or stainless-steel containers for water and storage. Again, BPA-free alternatives my not be any better, and could be worse.
  • Use cotton cloth napkins and kitchen towels instead of paper napkins and paper towels.
  • Cut up old cotton tee shirts, towels, bed sheets, and diapers to make disposable or washable toilet paper sheets. Place a diaper pail or washable waste can next to the toilet.  When you run a hot wash, toss them in. (Your mother managed, so can you).
  • Pee in the shower. It’s not as grody as it sounds. Pee as soon as you get in, and by time you soap up and shave, all will be fine.
  • Buy cotton hankies to blow your nose.
  • And of course, never, ever touch cash register receipts. Simply decline them, or wear disposable gloves. You may also want to discuss this with your merchant for their protection as well. Many stores have made changes because of this.

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

Follow Elyn on Facebook

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[i] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649250/

Other resources:

Science Daily

Science Daily

 

Note: IBC, an aggressive, metastasis-associated, therapy resistant type of breast cancer, is often resistant to radio-therapy and may actually progress with chemotherapy.

  1. Creighton CJ, Li X, Landis M, et al. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A 2009;106:13820-13825.

Vitamin D Better than Aromatase Inhibitors

In Alternatives to Hormone Therapy for Breast Cancer, Alternatives to Tamoxifen, Breast Cancer, Uncategorized on October 1, 2017 at 9:49 am

Pretty much every medical journal has posted research associating high vitamin D levels with a reduced risk of many cancers. Recent research, however, takes things a step further by showing that vitamin D actually reduces circulating estrogen levels, which has been found to reduce breast cancer risk and the progression of the dis-ease.  Excitingly, this may offer women an safer alternative to aromatase inhibitors.

Research done in 2016 at the Fred Hutchinson Cancer Research Center found that those with the greatest increase in vitamin D blood levels had the greatest reductions in blood estrogens. The randomized, controlled, clinical trial involved over 200 women who had insufficient D levels.  At the end of the year-long study, those whose D levels rose the highest had a corresponding reduction in estrogen levels. This study suggests that vitamin D supplementation may be a practical alternative to estrogen-lowering drugs, such as aromatase inhibitors.

Studies also show that natural progesterone offsets the effects of estrogen, and in doing so, reduces cancer risk. This is because progesterone hinders the growth of cancer cells, sort of putting the brakes on estrogen. However, it has been found that a lack of vitamin D reduces the benefits of progesterone.

Importantly, both progesterone and vitamin D regulate gene expression, and both have a positive fundamental effect on cell differentiation and growth, with anti-oxidative and autoimmune anti-inflammatory mechanisms. Therefore, it is important to maintain adequate levels of both progesterone and vitamin D.

Unfortunately, while natural progesterone has an anticancer effect, synthetic progesterone (found in birth control pills and hormone replacement supplements) does not. This is because unlike natural progesterone, synthetic versions do not stimulate activation of the P53 gene [i] (which is the tumor-suppressor gene involved that protects cells from becoming cancerous and orders damaged cells to self-destruct)), and as such, have not been found to inhibit cancer development.

If present, synthetic progesterone will occupy the progesterone receptors, preventing natural progesterone from occupying those receptors. In order for natural progesterone to facilitate the production of P53, it must attach itself to progesterone receptors. If synthetic progesterone (again, which does not stimulate the production of P53) is present on the receptors, natural progesterone will not be able to occupy the receptors. For more information on P53, please click HERE. For a deeper understanding of progesterone, please read my article The Truth About Progesterone and Breast Cancer.

Recent research shows (and this author believes) that blood levels should be 70-100ng/ml  and not the 30ng/ml most labs and doctors regard as adequate. The minimum daily dose required may well be 5000iu’s per day, although the latest research indicates it could be more like 10,000iu’s per day (I personally require even more than that).

Some doctors warn of toxicity risk but studies have found that even an intake of up to 40,000iu’s vitamin D per day is unlikely to result in vitamin D toxicity. [ii]  Just be sure to drink plenty of clean water and consume a healthy diet, which I recommend anyway. Despite the fact that more people are now taking vitamin D supplements, it’s rare to find someone with very high blood levels of this vitamin.

Cholesterol’s Role

Both progesterone and vitamin D3 are manufactured from cholesterol. Progesterone is primarily produced by the adrenals and ovaries. Vitamin D3 is made by the action of UVB sunlight as it strikes the cholesterol covering our skin—assuming you have not doused yourself with chemical or even non-chemical sunscreen. The moral of the story, as they say, is not to be so aggressive in reducing healthy cholesterol, and you might consider leaving the sunscreen home.

While vitamin D shows promise in the efforts to lower estrogen, please know that there are many natural substances that can be employed. It would be my recommendation not to rely solely on vitamin D, but rather to devise a comprehensive plan.  This is especially true as many people don’t actually have high estrogen levels, but rather are deficient in progesterone (and therefore are still estrogen dominant). For more information on natural approaches to anti-hormone therapy, please click HERE.

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

Follow Elyn on Facebook

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[ii] https://www.ncbi.nlm.nih.gov/pubmed/21378345

[i] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2882298/

Cancer-Busting Sweet Potato Salad

In Anticancer foods, foods for colon cancer, foods for breast cancer, Breast Cancer, Cancer, Uncategorized on September 30, 2017 at 12:50 pm

Sweet potatoes are delicious, satisfying, and easy to prepare.  Looking for a great tail-gate recipe? Try this cancer-fighting dish that will be sure to wow your taste buds and your friends.

Ingredients

3 pounds sweet potatoes (about 3 or 4 medium), peeled and cut into ½- 3/4

inch chunks

3 Tablespoons organic red wine vinegar

2 Tablespoons freshly squeezed orange juice

1 teaspoon finely grated orange rind zest (a microplane grater works well for this)

1 scallion, sliced on a diagonal

Course Celtic sea salt

¼ cup organic extra virgin olive oil

Freshly ground pepper

1 scallion, dark part only, sliced diagonally or 3 tablespoons chopped chives, for garnish

Preparation

  • Bring a large pot of filtered water to a boil; add potatoes. Bring back to a boil, reduce heat, and simmer for 5 minutes. Drain.
  • Whisk vinegar, zest, juice, scallion and ¾ tsp salt. Slowly add and whisk in oil.  Season with pepper.  Toss and chill. Garnish with sliced scallions or chopped chives.

Why eat it? Check out what it has to offer you….

Sweet potatoes have many health benefits. They are high in various B vitamins as well as vitamins A, C, and D. They also offer potassium and magnesium. Sweet potatoes are rich in carotenoids, powerful antioxidants which protect our eyes and boost immunity.

Notably, despite being “sweet”, sweet potatoes do not cause blood sugar spikes. Their natural sugars are slowly released into the blood stream.

Orange zest –the oils from orange zest are anti-fungal, immune boosting, antibacterial, and offer many anticancer properties.  Numerous studies have found that the d-limonene in orange oil inhibits the growth of cancerous cells.

Scallions are loaded with vitamin A and contain flavonoids that act as antioxidants (such as lutein, zeaxanthin, and carotenes) which work together to protect the body against various cancers.

Chives—compounds in chives reduce the damage caused by free radicals in the body.  Such molecules are involved in the onset of various cancers. Studies have shown that regular consumption of chives (a member of the allium family) reduces risk of stomach, breast, prostate and many other cancers.

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

Follow Elyn on Facebook

Follow Elyn on Linkedin