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Archive for the ‘Alternative Cancer Therapies’ Category

Natural Alternatives to Hormone Therapy for Breast Cancer

In Alternative Cancer Therapies, Alternatives to Hormone Therapy for Breast Cancer, Alternatives to Tamoxifen, Anticancer foods, foods for colon cancer, foods for breast cancer, Breast Cancer, foods that target cancer stem cells, Healing Cancer Naturally, Hormone Balance, Natural Alternatives to Aromatase Inhibitors, Tamoxifen on April 14, 2017 at 9:29 am

Many women choose to skip hormone therapy for breast cancer in favor of natural alternatives. This is because many don’t believe that tamoxifen, for example, is actually the wonder drug it is claimed to be. Others are terrified about the harm that this drug  (and others) can do, and do not feel the purported benefits justify the risks. Importantly, many women have come to realize that the statistics provided just don’t add up.

Tamoxifen vs. Flaxseed

Tamoxifen vs. Nature, the Choice is Yours

The reality of the small absolute percentages is something to keep in mind when your oncologist is spewing statistics.  It’s frightening enough to be told you have breast cancer without having statistics thrown at us that are taken out of context. A statistic that is often quote to women advised to take tamoxifen is that it will cut their recurrence risk in half. In reality, that half may only represent a single digit decrease.  For some excellent articles on this please see the resource section below. It is also important to know that many women who take tamoxifen have recurrences anyway, and also that there are indeed significant risks to taking this drug.

 Progesterone and the Hormonal Dance

When estrogen is too high and progesterone is too low, we have a condition known as estrogen dominance.  When estrogen dominates, we have an increased risk of breast cancer. However, we need estrogen, so the goal should not be to block it (with aromatase inhibitors), but rather to reduce it (if necessary) while increasing progesterone. Importantly, very few doctors actually test hormone levels before ordering tamoxifen or aromatase inhibitors.

Unfortunately, most women are deficient in progesterone. Stress is the number one reason for reduced progesterone. When we are stressed, adrenaline and cortisol rise and progesterone levels fall. This is because under stress, the body will always utilize the available pregnenolone to produce cortisol instead of progesterone.  One of the other main reasons for progesterone deficiency is the blocking of ovulation, which is done with oral contraceptives. Oral birth control pills suppress a woman’s own production of progesterone, which could result in a lifetime of progesterone deficiency. This topic will be explained further in my next post.

Making Progesterone…

The body uses cholesterol to make progesterone. In short, cholesterol makes the hormone pregnenolone, which is then converted into progesterone. (Pregnenolone is also the precursor for other hormones such as estrogen, cortisol, and testosterone). However, the body only makes so much pregnenolone, and the other hormones compete for this.

Many natural substances will help reduce estrogen dominance by managing estrogen and boosting progesterone levels. While no foods contain progesterone, certain micro-nutrients in them can help boost levels. For a more complete list, see below, but consider foods rich in zinc, magnesium, vitamin C, B6, and sulfur.

Sulfur-rich cruciferous vegetables (broccoli, kale, cauliflower, etc.) are rich in glucosinolates, which activate phase 2 detoxifications in the liver. This helps to remove estrogen from the body and prevents it from circulating too long, keeping estrogen levels high. The sulfur helps boost progesterone levels.  For more information on the anti-cancer power of crucifers, please Click Here.

For information on reducing estrogen levels, please refer to your Estrogen and Detoxification Handouts.  If you are not currently a client of mine, you can request these tools via my Contact Page.

Many women are under the impression that progesterone supports the growth of breast cancer.  However, while synthetic progesterone does, in its natural form it is highly protective. For an in-depth discussion on this, please Click Here.

Recap of Natural Alternatives:

There are many things involved with ‘natural alternatives’. But again, one of the most important things with regards to estrogen is to raise progesterone (after all, we need estrogen for bone and heart health and over a hundred other necessary functions).  Below are some suggestions. Many of these things have already been recommended to you.  For more detail, please refer to your Estrogen and Detoxification Handouts as well as your overall protocol.

Try to include some of these items daily as well as throughout the day: (For supplement brand recommendations, please go to my Shop Page.  You should be able to find most items locally, but if not, there are links to Amazon.

  • Cruciferous vegetables and DIM—be sure you have adequate iodine in your diet as DIM and crucifers inhibit the uptake of iodine by the thyroid gland. For more detail on the importance of iodine, please refer to your Estrogen Handout.
  • Consume apples, onions, garlic, green tea, and other quercetin rich foods
  • Eat berries and pomegranate
  • Resveratrol –this is best gotten from red grapes and other foods, but fine to supplement if you prefer (do not take supplemental resveratrol with Salvestrols)
  • Herbs (fresh, dried, or essential oils) such as sage, rosemary, ginger, curcumin, thyme, basil, and ashwaganda
  • EFA’s from omega 3 fatty acids (please use caution with fish oil supplements as they can be toxic)
  • Licorice root –licorice root can lower estrogen while at the same time raising progesterone
  • Vitamin D
  • Vitamin E (mixed tocopherols or eat vitamin E-rich foods, such as nuts)
  • Selenium
  • Magnesium –reduces stress reactions and breaks down estrogen metabolites, reducing estrogen dominance
  • Vitamin C
  • Vitamin B6 (combats stress and helps the liver break down estrogen, reducing estrogen dominance)
  • Zeolites (for a discussion on this, please see my Shop Page)
  • Zinc
  • L-Arginine
  • Chinese Herbal Medicine
  • Healthy cholesterol (needed to make pregnenolone) from coconut oil, olive oil, eggs, avocado, and olives
  • Fiber-rich foods such as flax seed, quinoa, oats, and millet (see below for more on flax–just be sure to grind this fresh daily)

You will also want to make sure that your liver and gut are functionally efficiently as estrogen is metabolized in the liver and excreted out of the bowel. By enhancing liver function, more estrogen is broken down in the body, reducing the overall estrogen load. Nutrients derived from cruciferous vegetables help with the detoxification of estrogen trough the liver (see more below).

When the liver and colon have become sluggish due to low thyroid function, stress, and an overburden of toxins, the body cannot break down and remove excess estrogen adequately from the system. The excess unbalanced estrogen gets stored in the fat cells of breast tissues when it is not properly eliminated. Supporting the liver with detoxifying foods such as cruciferous vegetables (broccoli sprouts, cauliflower, and Brussels sprouts), onions, whey powder, and supplements such as N-acetylcysteine (NAC), Milk Thistle, and SAMe can be very helpful.

Lifestyle Choices for Balancing Hormones and Inhibiting Cancer

Hormones become out of balance when we subject our bodies to a lifestyle that includes refined and processed foods, inadequate exercise, poor quality sleep, and exposure to xenoestrogens.  It is important to remember that contrary to what you may have been told, breast cancer (and other hormonal cancers) are not just about estrogen. Below are some suggestions to support hormone homeostasis as well as inhibit the development or progression of cancer.

  • Consume phytoestrogens -phytoestrogens act more like estrogen blockers than like estrogen; they modulate the production, availability, and action of hormones and slow down cell division. In fact, phytoestrogens are not really estrogens; they are anti-estrogens that reduce estrogen activity in the body. Plant estrogens protect us from the stronger estrogens our bodies produce as well as the xenoestrogens (chemical estrogen)  found in environmental chemicals, such as BPA and chemicals in personal care products. Phytoestrogens actually contain compounds that have been shown to reduce the growth and spread of cancer cells. Soy and flax are excellent sources of phytoestrogens.
  • Soy blocks cancer-promoting estrogens from attaching to the estrogen receptors on breast cells. It has also been shown to stop tumor growth, prevent metastasis, and shut off new blood vessels in growing tumors. Fermented soy, such as tempeh and miso are preferred over unfermented versions such as tofu as the fermentation process increases free radical scavenging activity and removes the nutrient blocking effect that soy can have—the phytic acid in unfermented soy can block absorption of key minerals such as magnesium and zinc. Soy in a highly-processed form (like soy protein isolate, soy protein concentrate, soy cheese) should be avoided. Due to the fact that most soy is genetically altered, it is highly recommended to consume only organic. (I do take issue with tempeh as it is commonly ‘shrink-wrapped’ in plastic.)
  •  Flaxseed modulates the production, availability, and action of hormones—and does so much more. The lignans in flax lower the production of estrogen by blocking the aromatase enzyme (similar to aromatase inhibitors) and block the estrogen receptors (similar to Tamoxifen). When lignans are consumed, intestinal bacteria convert them into enterolactone and enterodiol, weak estrogens. They attach to estrogen receptors, stimulate them weakly and block estrogen binding. This prevents estradiol or estrone from attaching to the estrogen receptors and strongly stimulating them, and includes not just the estrogen we produce, but also environmental toxins, thus making breast tissue more resistant to these environmental toxins. One long-term study reported that relatively high circulating enterolactone levels are associated with lower risk of death after an early-stage breast cancer diagnosis. A 2003 study conducted by Lilian Thompson PhD showed that daily consumption of ground flax seed significantly reduced breast cancer tumor size. Please read my articles — Flaxseed: Better Than Tamoxifen and Demystifying Flaxseed and Estrogen.
  • Eat good food—a diet rich in whole, primarily plant-based foods will support the adrenals and pretty much every function of the body.
  • Exercise—it reduces stress and positively effects gene expression; helps to balance hormones.
  • Clean out the closets—replace health, home and beauty products with non-toxic alternatives. A quick visit to the Environmental Working Group website will enable you to evaluate the products you use.
  • REDUCE STRESS—stress challenges adrenal function and makes direct physiological changes to DNA, not to mention that it significantly raises estrogen levels and depletes progesterone. Engage in yoga, meditation, and other mind-body therapies such as Psychotherapy, EFT, EMDR, the Emotion Code, and others that release negative emotions and past traumas.
  • Drink clean liquids. Choose filtered water (remove chlorine, fluoride, and other toxins in tap water).
  • Avoid alcohol, but if you do drink wine, make it organic–you wouldn’t eat conventional grapes, so don’t drink conventional wine. And, while red wine is somewhat protective against breast cancer as its resveratrol and other anti-cancer compounds help to metabolize estrogen and activate the P53 gene, don’t go overboard.  Your liver has to process that alcohol and if you drink too much, it won’t be able to metabolize estrogen efficiently. For more on the pros and cons of alcohol, please Click Here.
  • Get more sleep—lack of sleep disturbs hormone balance. Try to get to sleep by 10 pm as melatonin production peaks between 10 pm and 2 am. Melatonin stimulates tumor-suppressor genes and counteracts the effects of aggressive estrogens, including xenoestrogens. Cell phone EMF exposure can suppress the production of melatonin—limit use before bed (unplug 1-2 hours before going to bed) and do not keep them near your bed, and preferably out of your room.
  • Go with your gut, take a probiotic. Probiotics support gut bacteria and improve digestion, helping to prevent constipation. This is important because when stool remains in the bowel for extended periods of time, excess estrogen is re-absorbed and re-circulated into the bloodstream. Plus, immune function depends on healthy gut micro flora—and gut flora effects cancer genes too!
  • Consume GLA (gamma-linoleic acid), which is found in evening primrose oil and in hemp seeds. Research shows that this type of omega-6 may support healthy progesterone levels.
  • Eat turmeric or take supplements as turmeric effects estrogen receptor positive cancer cells.
  • Eat zinc-rich foods such as pastured eggs and meats and sprouted seeds. Shellfish such as oysters are abundant in zinc but should be eaten only in moderation.
  • Eat onions, garlic, chives, and scallions which are rich in sulfur-containing amino acids and the powerful anti-oxidant quercetin that help the liver detoxify at a higher level and reduce the production of estrogen.
  • avocado kale salad

    Avocado Kale Salad with Tomatoes and Spro

    Eat more vegetables. Aim for 10-15 servings a day (at least one pound daily). This will help excrete estrogen so it doesn’t keep circulating in the body. Also, aim for 35-45 grams of fiber per day, achieving this goal slowly to avoid gas or bloating. This will also help to keep weight in check—overweight or obese people tend to have higher circulating estrogen. Combining various vegetables in one meal can be especially helpful. For information on food synergy, please Click Here.

  • Eat raw carrots– When carrots are well chewed or grated, they help to stimulate the intestines and reduce the re-absorption of estrogen and the absorption of bacterial carrottoxins. The fiber in raw carrots binds to excess estrogen, helping to safely remove it from the body.
  • Essential oils can also be quite helpful in the management of estrogen-receptor positive breast cancer. Essential oils prevent angiogenesis, stop metastatic growth, increase apoptosis, and do so much more. Once you get started with essential oils, you will find that most, if not all, contain powerful anti-cancer properties, including the balancing of hormones.
    • Clove oil –Research has revealed that the eugenol in clove not only inhibits cancer growth and promotes apoptosis (cancer cell death), but it also acts as an antagonist to estrogen.
    • Lemon and other citrus oils can help reduce circulating estrogen. [On a side note, the D-Limonene in lemon oil has many other impressive anti-cancer abilities: it inhibits cellular proliferation and tumor growth, promotes apoptosis, supports immune function, and stimulates the liver’s detoxifying systems– and so much more].
    • Thyme oil supports progesterone levels. Evening primrose oil and thyme together are very beneficial to help balance levels of progesterone.
    • Clary Sage oil helps balance estrogen levels whether you have too much or too little estrogen. You can use it with a carrier oil on your skin or hair. It also initiates apoptosis (programmed cell death). Clary sage also contains phytoestrogens which, like flaxseed, can block estrogen receptors. I suggest you rub a few drops into the soles of your feet before bed. This will help to balance your hormones as well as promote healthy sleep.
    • Myrrh and fennel are strong phytoestrogens. Myrrh clears excess estrogen and detoxifies the liver.
    • Sandalwood stops DNA from repairing itself (cancer DNA). Note: Cedarwood can be just as effective and is cheaper.
    • Mint is effective against numerous types of cancer, such as acute T-cell leukemia, brain tumors, prostate, breast, cervical, bladder, colorectal and pancreatic cancers.

ej pink two

Lastly, and I cannot stress this enough — breast cancer is NOT just about estrogen.  Cancer is a symptom of a complex problem. It is a multi-factorial situation that presents to reveal dis-ease within the mind, body, and soul.  Therefore, in order to heal, one must correct the issues that caused the symptom we know as cancer.

Please also read:

https://elynjacobs.com/2016/10/26/natural-alternatives-to-aromatase-inhibitors-2/

https://elynjacobs.com/2012/01/15/natural-alternatives-to-tamoxifen/

Resources: Understanding Statistics

http://cancercompassalternateroute.com/breast-health/tamoxifen-and-the-manipulation-of-statistics/

http://www.greenmedinfo.com/blog/tamoxifen-praised-life-saving-still-causing-cancer

https://thetruthaboutcancer.com/truth-about-tamoxifen-part-1/

Tamoxifen: What Difference Does It Really Make? 

Elyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website, www.elynjacobs.com. Elyn offers consults via Skype, phone or in person.

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Epstein Barr Virus and the Development of Cancer

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Anticancer foods, foods for colon cancer, foods for breast cancer, Breast Cancer, Uncategorized on January 24, 2017 at 4:02 pm

The Epstein-Barr Virus (EBV) is one of the most common viral infections in humans. It is also one of the most prolific–over 95% of adults carry this virus. While originally linked to lymphoma, subsequent research has linked EBV to stomach cancer, nasopharyngeal cancer, and many others, including breast cancer.

Once you are infected with EBV, it remains dormant in the body forever, often asymptomatic. For some, this will not be a problem.  For others, it can result in long-term consequences, including dramatically raising one’s risk of cancer as well as aggressive progression of the disease.

When reactivated, EBV can present with symptoms such as cold sores or flu-like symptoms. But again, often there are no symptoms—yet the virus is at work, leaving genetic scars on our cells. Molecules produced by EBV can send infected cells into overdrive, telling them to keep dividing.  Importantly, EBV does not initiate cancer on its own — there are other elements at play. It is a combination of genes and diet along with the EBV infection that create the perfect storm for cancer.

Herpetic viruses such as EBV are so often behind autoimmune disorders such as lupus, MS, and Hashimoto’s thyroiditis. Hence, many with autoimmune issues will also develop cancer.

The Immune System is Our First Line of Defense Against Infections

With EBV, it can also be a bit of the chicken and the egg theory.  Fighting the infection itself could exhaust the immune response, which might hinder detection and destruction of cancer cells, allowing them to replicate.  Or, it could be that an already weak immune system, combined with a poor diet, leaves the door open to infection and flare-ups of dormant Epstein Barr and the development and progression of cancer.

Researchers are working on ways to uncloak the virus to immune cells in hopes that this will rid the body of EBV, rather than leave dormant infection around to cause problems. Will that mean another controversial vaccine? Possibly.

Food Matters

However, there are many natural substances that can suppress viral reactivation. For more information on EBV and its link to cancer, please read the following article I wrote for The Truth About Cancer: Epstein Barr Virus Connection to Breast Cancer & Autoimmune Disorders. In it you will also learn about the triggers for reactivation as well as the dietary choices, supplements, and herbs that suppress the EBV and help your body defend itself against cancer.

Found this article helpful?  Please let me know.

Elyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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Other articles you might like:

Herpes Virus (CMV) Linked to Most Common Type of Childhood Cancer (ALL)

12 Things a Cancer Doctor Should Never Say

10 Questions to Ask BEOFRE Accepting Radiation Therapy for Cancer

12 Questions to Ask BEFORE Saying “Yes” to Chemotherapy Treatment

Girls, Puberty & Breast Cancer Risk: What Moms Need to Know Now

What Your Oncologist Isn’t Telling You About Chemotherapy and Radiation

Are You Magnesium Deficient? How to Know & What to Do About It

Tap Water? No Thanks Unless it is Filtered

In Alternative Cancer Therapies, Breast Cancer, Cancer on January 22, 2017 at 3:26 pm

One thing I say to all of my clients is NO TAP WATER (at least not unfiltered).  We really don’t know what is in our water. For most of us, we do know there is chlorine and a host of other chemicals. We can also be sure that some of us have traces of pharmaceutical drugs in our water.  Many of us also have fluoride in our water.

All of these toxic chemicals are in some way carcinogenic and must be avoided.  The best solution, in the perfect world, is to have a whole-house filter.  Always keep in mind that when you bathe, you inhale and absorb through the skin the chemicals in water.

But as the world is not perfect, at the very least, we should filter our drinking and cooking water.  

So, what are the options. Likely you have heard of Berkey systems.  This is a great option for those looking for reliable clean water.  The Big Berkey  system removes pathogenic bacteria, cysts, and parasites and reduces harmful chemicals such as herbicides, pesticides, and VOCs without removing beneficial minerals. Berkey offers ceramic and black filters, the later also filters out fluoride and arsenic. There are only two problems with the Berkey systems. One is that these are expensive. The other is that they can be a nuisance to clean.

41g1euwr4l-_sy300_Another option is the ZeroWater pitcher (which is what I use). The filters filter out over 99% of contaminants, including fluoride and lead, and the water tastes great.  I was really amazed.  The pitchers come with a TDS indicator (total dissolved solids) so you know when to change the filter.  I had fun with this gadget, and tested our tap, Poland Springs, and Mountain Valley Spring.  Well, of course you know that the tap failed. The Poland Springs passed, as well as the Mountain Valley. While not a fan of the plastic used for the Poland Springs bottles (Mountain Valley comes in glass), at least there did not appear to be nasty things in the water. Of course, I am not thrilled that the Zero pitcher is plastic, but to get around that you can immediately put the water in a glass jug.  One note—if you are considering the stainless-steel pitcher to avoid the plastic, don’t bother.  The inside is plastic, so unless you just prefer the look, again, not worth the extra money.

While Brita makes a good line of inexpensive water pitchers, their filters do not remove fluoride, lead, and other toxins. According to their site, it reduces chlorine taste and odor, copper, mercury, and cadmium.

Another option is water distillation (reverse osmosis), which removes, fluoride, chlorine, lead, pesticides, etc. The price varies, but ranges from $200 to well over $1000.

Don’t want to filter your water?  Consider Mountain Valley Spring Water.  The water is delicious. The only drawback is that you have to stack the boxes someplace. Plus, even though we recycle the bottles, it still seems wasteful. Still, they are portable and great bedside, especially if you are like me and tend to knock over water glasses at night. One potential issue is that the water has a high alkaline ph. While this sounds like a good idea, drinking too much high alkaline water can disrupt the body’s natural ph. We need stomach acid to digest our food, so try not to drink high alkaline water before a meal or even all day long. Hence I drink their water and use the Zero system as well.

 

mountain valley spring water

Elyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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What You Need to Know About Mutations in the p53 Cancer Tumor Suppressor Gene

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Anticancer foods, foods for colon cancer, foods for breast cancer, colon cancer, High Dose Vitamin C and Cancer, Radiation on January 3, 2017 at 2:34 pm

The word mutation just doesn’t sound like something good. By definition, a mutation is a permanent change in DNA. Mutations, for the most part, are harmless except when they lead to tumor formation. 

Likely you have heard about BRCA mutations. BRCA genes are tumor suppressor genes. BRCA mutations can increase one’s risk for cancers of the breast and ovaries. However, these mutations are only responsible for about 5-10% of all breast cancers and about 15% of ovarian cancers. But, the little-known p53 mutation affects far more people. About 50% of all cancers have a mutated p53 gene.

What is P53?
The p53 protein is located in the nucleus of cells throughout the body, where it attaches (binds) directly to DNA. (It is actually the TP53 gene that provides instructions for making the tumor protein p53 but for simplicity, I will say p53.) P53 regulates cell division by keeping cells from growing and dividing too fast or in an uncontrolled way.

P53 plays a critical role in determining whether damaged DNA will be repaired or a damaged cell will self-destruct (undergo apoptosis). If the DNA can be repaired, p53 activates other genes to fix the damage. If the DNA cannot be repaired, this protein prevents the cell from dividing and signals it to undergo apoptosis. By stopping cells with mutated or damaged DNA from dividing, p53 helps prevent the development of tumors.

Mutated P53
P53 mutations lead to a version of p53 that cannot regulate cell growth and division effectively. Specifically, the altered protein is unable to trigger apoptosis in cells with mutated or damaged DNA.

DNA can be damaged by agents such as toxic chemicals, radiation such as gamma rays, X-rays — even UV light can interact with compounds in the cell generating free radicals which cause chemical damage to DNA.

Since all cells in our body contain DNA, there are lots of places for mutations such as p53 to occur. When p53 does not operate properly, damaged DNA can replicate, producing mutations and DNA rearrangements that contribute to the development of a highly transformed, metastatic cell. Many cancer cells inactivate p53, allowing the cells to evade death and continue proliferating up to becoming a tumor.

Mutant p53 proteins not only lose their tumor suppressive activities but often escalate the development of cancerous tumors by providing them with growth and survival mechanisms. Interestingly, mutations in the p53 gene have been shown to occur at different phases of the cancer process, contributing to tumor initiation, promotion, aggressiveness, and metastasis.

P53 mutations contribute to risk of brain tumors and breast, prostate, colon and other cancers. Mutations in p53 gene usually correlate with poor outcome and early recurrence in cancer.

Enough of the bad news.

The Good News
What is really exciting is that this repair gene, p53, which protects cells from becoming cancerous, can be highly activated by many natural substances—substances that do not have the negative side effects of drug therapies. The ability to activate p53 within cells may halt cell proliferation, or even cause cancer cell death.

 

watercressFor example, cruciferous vegetables (especially watercress with its high content of PEITC) have been found to support p53. PEITC (phenethylisothyanate) decreases the levels of mutated p53 and helps to restore the normal activity of this protein. Vitamin C is another promoter of P53, which is one of the reasons intravenous Vitamin C (IVC) and high-dose oral C therapies are so effective against cancer.
The resveratrol in red grapes and red wine (organic please, and research shows dark, red wines are best) also activates the P53 gene. IP6 has been shown to alter the expression of p53. Zinc helps protect the p53 gene against cancer-forming mutations. Selenium can activate p53 in response to genetic damage, helping the cell to repair its DNA. Herbs such as sage, rosemary, ginger, curcumin, and ashwaganda support p53. Thymoquinone extracted from black seed triggers apoptotic cell death in colorectal and other cancers cells via the p53- dependent mechanism. Anthocyanins, abundant in red  onions, inhibit the damage that impaired p53 can cause on cells and tissue. Anthocyanins are also found in blackberries, blueberries, purple grapes, eggplant, and avocado.

P53 Supporters:
• Cruciferous vegetables, especially watercress
IP6
Resveratrol
• Herbs such as sage, rosemary, ginger, curcumin, and ashwaganda
• EFA’s from omega 3 fatty acids (please use caution with fish oil supplements as they can be toxic). For a plant based formula, you could take BodyBio Balance Oil.
• Licorice
• Mistletoe
Vitamin D
Selenium
• Vitamin C
Zinc
Black Seed
Clinoptilolite (a special form of Zeolite)
On the other hand, processed foods, refined flours, and sugars will impair P53. Smokey flavoring and smoked foods can also damage DNA. Chemicals such as benzene and perchloroethylene, two volatile organic compounds, negatively affect p53, possibly causing them to stimulate rather than suppress cell proliferation.

The late Integrative Oncologist Dr Mitchell Gaynor, MD was famous for his passion for explaining that we can change the way our genes behave by making good dietary choices. For more gene-changing foods and lifestyle habits read Dr. Gaynor’s book, The Gene Therapy Plan, Taking Control of Your Genetic Destiny with Diet and Lifestyle.

P53 and BRCA are not the only genetic mutations that increase cancer risk. For example, mutations in th e CHEK2 gene are associated with an increased risk of developing many types of cancer, including breast, colon, prostate, and other cancers — sometimes at young ages. If you have a history of hereditary cancer you might benefit from genetic testing for CHEK2 and others.

Testing
You can request to be tested for the p53 mutation. The test is called the p53 Gene Mutation Analysis, Cell Based, offered by labs such as Quest Diagnostics. If your insurance company does not accept Quest or another lab that offers this test, you can petition your carrier for a Network Gap Exception.
You may need to consult a genetic counselor if your oncologist does not routinely check for mutations as these tests are not part of your typical pathology report.

Found this article helpful?  Please let me know.

 

Elyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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http://www.ambrygen.com/tests/chek2-related-cancer
http://www.nbs.csudh.edu/chemistry/faculty/nsturm/CHEMXL153/DNAMutationRepair.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827900/
https://ghr.nlm.nih.gov/gene/TP53
https://www.ncbi.nlm.nih.gov/pubmed/14608114
http://www.ambrygen.com/tests/chek2-related-cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135636/

Why You Need to Know about IP-6 if You Have Cancer

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Anticancer foods, foods for colon cancer, foods for breast cancer, Uncategorized on December 17, 2016 at 5:38 pm

ip6The B-vitamin inositol and its derivative IP-6 (Inositol hexaphosphate) is an anti-oxidant with many health benefits for human health. It is important for regulating vital cellular functions such as signal transduction, cell proliferation, and differentiation. IP-6 offers significant protection against cancer and it also helps to lower cholesterol, prevent kidney stones, and reduce the complications of cardiovascular disease.

Recently IP-6 has received much attention for its role in cancer prevention and control of tumor growth, progression, and metastasis. IP-6 works by increasing your body’s Natural Killer Cell activity. NK cells target cancerous cells as well as invaders such as virus, bacteria, fungus, and molds. NK cells are also a part of the Th1 immune system, which is commonly depressed in cancer patients. IP-6 has also shown to revert cancer cells back  to normal by its ability to increase the differentiation of malignant cells.

IP-6 is a selective agent against cancer cells. Cancer cells are high in iron content, so IP-6 directs most of its attention to abnormal cells since IP-6 acts as a selective iron chelator. It removes iron from tumor cells (stealing one of its major food sources) which deprives them of their primary growth factor. Importantly, IP-6 does not remove iron from red blood cells which are tightly bound to hemoglobin. Therefore, unlike cancer drugs, healthy cells are not affected by IP-6.

IP-6 and Tumor Suppressor Genes
IP6 has been shown to alter the expression of proteins produced by the p53 (TP53) and p21 genes (cancer suppressor genes) that control cancer growth.

The p53 gene regulates cell division by keeping cells from growing and dividing too fast or in an uncontrolled way. Inactivation of the p53 tumor suppressor is a frequent event in tumorigenesis. In most cases for those with cancer, the p53 gene is mutated, and the accumulation of those mutated proteins is regarded as a hallmark of cancer cells. Mutated P53 cannot regulate cell growth and division effectively. Specifically, the altered protein is unable to trigger apoptosis in cells with mutated or damaged DNA. As a result, DNA damage can accumulate in cells (this is common with CHEK2 mutations).

When the DNA in a cell becomes damaged by things such as toxic chemicals or radiation, P53 plays a critical role in determining whether the DNA will be repaired or the damaged cell will self-destruct (undergo apoptosis). If the DNA can be repaired, p53 activates other genes to fix the damage. If the DNA cannot be repaired, this protein prevents the cell from dividing and signals it to undergo apoptosis. By stopping cells with mutated or damaged DNA from dividing, p53 helps prevent the development of tumors.

Mutant p53 proteins not only lose their tumor suppressive activities but often escalate the development of cancerous tumors by providing them with growth and survival mechanisms. Interestingly, mutations in the p53 gene were shown to occur at different phases of the cancer process, contributing to tumor initiation, promotion, aggressiveness, and metastasis.
P21 is controlled by p53, and can be significantly correlated with lymph node metastasis, distant metastases, advanced TNM stage (a classification of cancer staging that stands for: tumor size, describing nearby lymph nodes, and distant metastasis), depth of invasion, and overall survival rate. To read more on p53, click HERE.

IP-6 also inhibits MMP-9 secretions. Matrix metalloproteinase-9 (MMP-9) plays important roles in tumor invasion and angiogenesis. Secretion of MMP-9 has been reported in various cancer types including lung cancer, colon cancer, and breast cancer.

Circulating Tumor Cells

It is important to remember that it is not the primary tumor that kills us, but rather the metastatic disease post-treatment that kills us. When cancer spreads to other areas in the body it is called metastasis. In order to spread, a cancer cell must first detach from the primary cancer and move though the wall of a blood vessel to get into the bloodstream.
These mobile cancer cells are called circulating tumor cells (CTCs). When CTC’s enter the bloodstream, the circulating blood sweeps them along until they stick somewhere, usually in another opportunistic position that enables it to lodge and multiply.
This is a complicated journey as the immune system is designed to rid the host of these cells. Therefore, some of the time CTC’s are not problematic. However, in a host (you) with cancer and therefore with the likelihood of a weak or dysfunctional immune system, well, you can see how the risk increases. (A simple blood test can determine the existence of circulating tumor cells in the body. At this time, the only lab I know of that will readily offer this test is Quest Diagnostics. If your insurance company does not use Quest, you may need to petition them for it.)
Hence, reducing circulating tumor cells (CTC’s) and using other strategies to prevent metastases should be the focus of treatment once individuals have treated the primary tumor and are addressing the primary cause of the dis-ease. IP-6 seems to be the new kid on the block when it comes to targeting CTC’s (along with Modified Citrus Pectin*).

It is well known that the potent antioxidant and immune enhancing properties of IP6 can play a vital role in the prevention and treatment of cancer cells. It Sadly, IP-6 goes unused as a cancer treatment, which makes no sense. Further, IP-6 enhances the efficacy of cancer drugs such as Adriamycin (a popular chemotherapy) and tamoxifen. Yet again, it goes unused by the traditional medical community even as an adjunct therapy.
It is up to you, the educated patient, to be sure you are taking advantage of all that is available to you to heal from your cancer.

Summary of IP-6 benefits:
• Inhibits cell proliferation and progression
• Helps stop cancer growth
• Induces differentiation of malignant cells
• Supports the p21 and p53 genes (tumor suppressor genes) that control cancer growth
• Inhibits metastasis by interfering with the CTC adhesion, migration, and invasion
• Induces apoptosis (cell death) in many cancer cell lines
• Inhibits angiogenesis (new blood vessel growth for tumors)

IP-6 is easily absorbed into the gastrointestinal tract and has been found to be safe. It can be found in many plant sources and in high-fiber foods such as seeds, bran, cereals and legumes. It can also be taken in supplement form. You can find IP-6 in most health and drug stores. However, don’t get the cheap versions of this stuff—be sure to buy a reputable brand. For your convenience, you can find IP-6 here on Amazon.

*Modified Citrus Pectin (MCP): Helps with detoxification and inhibits circulating tumor cells (CTC’s) from latching onto the lining of blood vessel walls, reducing the risk of metastases.

https://www.ncbi.nlm.nih.gov/pubmed/17044765
https://www.ncbi.nlm.nih.gov/pubmed/14608114
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135636/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3126032/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2722839/

Found this article helpful?  Please let me know.

 

Elyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She brings a plethora of knowledge to her practice and will help you think outside the box so you can incorporate every lifeline you may need for long term survival. Elyn is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. She is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

Elyn does not endorse alternative modalities as a cure for cancer. She provides information solely for educational purposes only.
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Energy Healing Holiday Special

In Alternative Cancer Therapies, Uncategorized on December 14, 2016 at 8:02 pm

Wondering what Energy Healing can do for you? April Fontana, known as The Oracle Healer, is offering a great special right now. Get 20 mini sessions (tune ups) and one remote healing for just $800. As you may remember, April was on my healing team and still is–for me and my family. This offer is limited to the first 10 people who sign up. For more information, please contact April Fontana.

 

april

Want more information on Alternative Therapies? Visit my Alternatives Page.

Want to read how alternatives helped me to heal?  Read my Story.

Elyn
~~If you don’t know your options, you don’t have any~~
Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She brings a plethora of knowledge to her practice and will help you think outside the box so you can incorporate every lifeline you may need for long term survival. Elyn is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. She is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

Elyn does not endorse nor does she benefit from alerting her readers to alternative modalities. She provides information solely for educational purposes only. 

Follow Elyn on Facebook

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Must Reads for Every Cancer Patient or Survivor

In Alternative Cancer Therapies, Books for Cancer Patients, Cancer, Healing Cancer Naturally, High Dose Vitamin C and Cancer on November 28, 2016 at 2:23 pm

Right now Amazon is taking $10 off book purchases over $25. Just use the code HOLIDAYBOOK.

My Recommendations:

LifelinesLifelines to Survival: A New Approach to Personalized Care $17.  To read my review of this book, click HERE.

Orthomolecular Medicine for Everyone  A great read for those who value nutrition as good medicine.  You will learn about high-dose vitamin therapies and why they work for many. $15.

childhood-disruptedChildhood Disrupted: How Your Biography Becomes Your Biology, and How You Can Heal. While we cannot change what happened in our childhood, we can alter its effects on us –something most oncologists completely overlook as a critical part of treatment and recovery. Childhood Disrupted also explains how to cope and heal from these emotional traumas. $11. To read my post on this book, click HERE.

Radical Remission: Surviving Cancer Against All Odds $10

Breast cancer booksWaking the Warrior Goddess, Third Edition: Dr. Christine Horner’s Program to Protect Against & Fight Breast Cancer $22

The Whole-Food Guide for Breast Cancer Survivors: A Nutritional Approach to Preventing Recurrence (The New Harbinger Whole-Body Healing Series) $13

Eat Dirt: Why Leaky Gut May Be the Root Cause of Your Health Problems and 5 Surprising Steps to Cure It $17

The Truth about Cancer: What You Need to Know about Cancer’s History, Treatment, and Prevention $15

Essential oils and Cancer  $7

Life Over Cancer: The Block Center Program for Integrative Cancer Treatment $22

The Iodine Crisis: What You Don’t Know About Iodine Can Wreck Your Life $17

gaynor GTPThe Gene Therapy Plan: Taking Control of Your Genetic Destiny with Diet and Lifestyle $14

Beyond the Magic Bullet $30

Beating Cancer With Nutrition  $19

More …

Cancer Report: The Latest Research – How Thousands are Achieving Permanent Recoveries

The Etiology of Breast Cancer: Endogenous and Exogenous Causes

Killing Cancer Not People New 3rd Edition

 You Are the Placebo.  Is it possible to heal by thought alone—without drugs or surgery? The truth is that it happens more often than you might expect. In You Are the Placebo, Dr. Joe Dispenza shares numerous documented cases of those who reversed cancer, heart disease, depression, crippling arthritis, and even the tremors of Parkinson’s disease by believing in a placebo.

The Hidden Connection: Discover What’s Keeping You from Feeling Happy, Healthy and Symptom-Free

Miracle Survivors: Beating the Odds of Incurable Cancer

Cancer Free!Cancer Free, Are You Sure? While many people are comforted by the words “you are cancer free”, it is imperative to know that an all-clear PET or CT is often meaningless.  Read this amazing book to learn more.

 Recommended Cookbooks:

The Oh She Glows Cookbook: Over 100 Vegan Recipes to Glow from the Inside Out

The Cancer-Fighting Kitchen: Nourishing, Big-Flavor Recipes for Cancer Treatment and Recovery

Vegan Richa’s Indian Kitchen: Traditional and Creative Recipes for the Home Cook

 

 

Natural Alternatives to Aromatase Inhibitors

In Alternative Cancer Therapies, Alternatives to Hormone Therapy for Breast Cancer, Alternatives to Tamoxifen, Natural Alternatives to Aromatase Inhibitors, Tamoxifen, Uncategorized on October 26, 2016 at 12:30 pm

Unfortunately, many oncologists are under the misbelief that estrogen is the enemy, and often misrepresent estrogen as the root cause of one’s cancer. Perhaps your doctor recommended an aromatase inhibitor to get rid of this ‘dangerous’ estrogen. And most likely if you are reading this post it is because you are concerned about the side effects or the resulting effects of these drugs. Or maybe you started on one, feel terrible and are seeking alternatives. Here is what you need to know before you get led down that ‘primrose path’.

The Role of Aromatase Inhibitors

Aromatase inhibitors drugs (AIs) such as Fermara, Aromasin and Arimidex, stop the production of estrogen in postmenopausal women. More specifically, they block the enzyme aromatase, the enzyme responsible for the biosynthesis and balance of estrogens.

However, while AIs have been found to prevent some breast cancer recurrences, they have not been found to actually prolong life (meaning you don’t die of the breast cancer, but rather from aromatase inhibitor use). This is due to the resulting effects—as I like to call them—particularly heart damage. They also reduce quality of life due to side effects such as the never ending flu symptoms, hair thinning and loss, vaginal bleeding, skin rashes, joint pain, stiffness and swelling (severe enough to require pain medication), hot flashes and night sweats, vaginal dryness, nausea, and headaches. Women may also feel tired and lethargic while on the drug, experience breathing difficulties, depression, and mood swings, tightness in the chest, and because of the loss of the estrogen, bone thinning (think broken bones). Not to mention that breast cancers eventually develop resistance to drug therapies.

Just because your doctor prescribed an AI, doesn’t mean that it is right for you. Making the right decision for you, for your body, is bigger than just accepting doctor’s orders. Masking a problem with an aromatase inhibitor is not the same thing as correcting the problem. And even if reducing aromatase might be helpful for you, yes, there is a better way.

Your doctor just might need to better understand the role of hormones in breast cancer. While oncologists know how estrogen receptors fuel the growth of cancer cells, they seem to know a lot less about what progesterone receptors do in those same cells.

The Scoop on Estrogen  

It is time to set things straight. We need estrogen for aiding in the prevention of heart disease and for strong, healthy bones–estrogen is essential to the health of all parts of your body, from your eyes to your heart to your brain to everywhere else. We can we live with our estrogen, we need it; in fact, we can’t live without it. However, estrogen must be balanced by progesterone, which will be discussed below.

Hormonal imbalances have reached epidemic proportions in most developed countries over the last several decades. Due to poor diets, lack of exercise, a rise in obesity levels, the widespread use of hormone-altering chemicals, and other factors, many women suffer from chronically higher than normal estrogen levels and much lower than normal progesterone levels. Age plays a role as well, as after the age of 45 or so, estrogen levels decline, but progesterone plummet even more so. In other words, many women are in chronic states of estrogen dominance. This is one of the key reasons why breast cancer rates are as high as they are.

You see, while certain estrogens can stimulate cancer cell proliferation, progesterone inhibits this from happening. Progesterone acts as an antagonist to estrogen. When there is unopposed estrogen because of a deficiency in progesterone, there is an increased risk of developing cancer. When progesterone is raised to healthy levels relative to estrogen, it turns on genes that can prevent breast cancer from occurring and reduces the size of existing tumors.

So here is what your doctor needs to know. When adequate progesterone is present, the progesterone receptors attach themselves to the estrogen receptors. Once this happens, the estrogen receptors stop turning on genes that promote the growth of the cancer cells. Instead, they turn on genes that promote the death of cancer cells (known as apoptosis) and the growth of healthy, normal cells. In other words, the progesterone receptors activate genes such as p53 that promote apoptosis. Apoptosis enables the body to “kill off” many cancer cells before they develop into tumors. On the other hand, the estrogen receptors directly bind and inactivate p53, which otherwise would restrain the replication of damaged cells. The P53 gene is the primary gene that protects men from prostate cancer and women from breast cancer. So naturally we want to support the p53 gene (which is really the P53 protein).  You can read more about how to support the P53 gene in my Estrogen Handout

It is important to note that progesterone also helps to offset xenoestrogens (chemical estrogens which are foreign to the body) which are difficult for the body to detoxify.

However, it is very important to understand that estrogen, in general DOES NOT CAUSE BREAST CANCER. Cancer is a multifactorial disease– genetics, lifestyle factors, infection, and especially environmental and emotional toxins all play a role. But since we cannot efficiently metabolize xenoestrogens and because of the overall estrogen dominance, inhibiting aromatase is often a good idea. It may not be that you have too much estrogen or that you need to block the estrogen receptors, it could just that you don’t have enough progesterone.

For a more in-depth discussion on how estrogen and progesterone affect the expression of tumor suppressor genes and what you can do to make the expression favorable, please request my Estrogen and Detoxification Handouts.

Is There a Natural Alternative to Aromatase Inhibitors?

Progesterone’s opposition to the effects of estrogen is so basic, that I fail to see how oncologists do not see progesterone as being the ultimate antiestrogen. Given that progesterone stops cell division by opposing the effects of estrogen, and given that it is not in our best interest to completely block estrogen, the real goal of the oncologist should be to reduce estrogen while increasing progesterone.

 While there is no one magic pill for this, a comprehensive strategy will help to support the tumor suppressor genes by supporting the production of progesterone and inhibiting the estrogen-fueled proliferation of cancer cells.  What you eat, do, and think all play a significant role.

  • Eat good food—a diet rich in whole, primarily plant-based foods will support the adrenals and pretty much every function of the body.
  • Consume button mushrooms, rosemary, celery, parsley, pumpkin seeds, raw whole carrots, citrus and other essential oils, oregano, thyme, rosemary, sage, turmeric, onions, garlic, chives, and scallions which inhibit estrogen and boost progesterone levels.
  • Consume phytoestrogens -phytoestrogens act more like estrogen blockers than like estrogen; they modulate the production, availability, and action of hormones and slow down cell division. Flaxseed is especially important. Flaxseed: Better Than Tamoxifen and Demystifying Flaxseed and Estrogen.
  • Consume cruciferous vegetables as nutrients derived from them help with the detoxification of estrogen trough the liver. Note that DIM and raw crucifers can inhibit iodine and the thyroid. Estrogen also inhibits the absorption of iodine and impacts thyroid levels. Have your iodine and thyroid levels checked and supplement with iodine if necessary.
  • Eat more vegetables. Aim for 15 servings a day (at least one pound daily). This will help excrete estrogen so it doesn’t keep circulating in the body.
  • Anti-inflammatory foods that are rich in saturated and omega-3 fatty acids such as 100% organic, grass-fed beef & dairy, organic poultry, wild-caught Salmon and wild game are anti-estrogenic. Plant based fats such as avocados, coconut oil and olive oil are all powerful anti-estrogenic superfoods.
  •  Take supplements such as DIM, zinc, Vitex Fruit (Chaste Tree), grape seed extract, magnesium, zinc, ginko biloba,vitamin E, and iodine.
  • Support liver function with milk thistle and other natural detoxifiers. Estrogen is metabolized in the liver. Fortifying the liver will help speed up estrogen clearance from the body. Estrogen that is not metabolized by the liver will continue to circulate, contributing to estrogen dominance.
  • If you are overweight, lose weight. Fat cells increase estrogen production. Increased weight often means insulin resistance and this is a common cause of high estrogen levels.
  • Exercise—it helps reduce stress and positively effects gene expression, and helps to balance hormones.
  • Clean out the closets—replace health, home and beauty products with non-toxic alternatives. A quick visit to the Environmental Working Group website will enable you to evaluate the products you use.
  • REDUCE STRESS—stress challenges adrenal function and makes direct physiological changes to DNA, not to mention that it significantly raises estrogen levels and depletes progesterone.
  • Avoid alcohol, but if you do drink wine, make it organic–you wouldn’t eat conventional grapes, so don’t drink conventional wine.
  • Get more sleep—lack of sleep disturbs hormone balance.
  • Go with your gut, take a probiotic. Probiotics support gut bacteria and improve digestion, helping to prevent constipation. This is important because when the stool remains in the bowel for extended periods of time, excess estrogen is re-absorbed and re-circulated into the bloodstream.

Estrogen is metabolized in the liver. Fortifying the liver will help speed up estrogen clearance from the body. Estrogen that is not metabolized by the liver will continue to circulate, contributing to estrogen dominance and raising the risk of hormonal cancers. Studies show that women with genetically impaired estrogen metabolism function may have a higher risk of breast cancer and may benefit from increased detoxification.

For more detailed information on aromatase inhibitors, natural alternatives to Tamoxifen, and detoxification strategies please request my Estrogen and Detoxification Handouts.

Read also Natural Alternatives to Tamoxifen 

Read 12 Things a Cancer Doctor Should Never Say, my most recent article on The Truth About Cancer website. Look for my upcoming article Emotional Trauma and Cancer: The Missing Link, in their October newsletter.

Read Mushrooms as well as the link in that post.

Note: This article is an updated version of my 2012 article.

This information is for educational purposes only. It is not intended to treat, cure, prevent or diagnose any diseases or conditions. The information in this post does not represent medical advice, and I encourage you to discuss this information with your integrative oncologist or naturopathic doctor. Always consult with a medical doctor before you consider any prescription or over the counter drug or herb.

Found this article helpful?  Please let me know.

 

Elyn
~~If you don’t know your options, you don’t have any~~
Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She brings a plethora of knowledge to her practice and will help you think outside the box so you can incorporate every lifeline you may need for long term survival. Elyn is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. She is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

 

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High Dose Vitamin C: The Other Cancer Therapy

In Alternative Cancer Therapies, Cancer, Healing Cancer Naturally, High Dose Vitamin C, High Dose Vitamin C and Cancer on September 17, 2016 at 10:17 am

Can Oral High Dose Vitamin C Kill Cancer Cells More Effectively than Intravenous C?

The use of High-Dose Vitamin C for cancer mitigation and management has been studied for years. Holistically minded professions use HDVC in conjunction with other innovative treatments to maximize effectiveness. Most of these doctors do not use traditional chemotherapy or radiation as they often cause permanent or even fatal side effects –these therapies destroy all cells, healthy and malignant, eventually leading to patient death.

Building on the work of Linus Pauling, who was recognized as the world’s foremost advocate of therapeutic vitamin C, significant research shows that high dose vitamin C (HDVC) effectively eradicates cancer cells while leaving healthy cells intact. HDVC has been used alongside cancer therapies (both conventional and holistic) since the 1970’s. While not considered to be a cancer cure, it is a powerful adjunctive therapy for cancer patients.

Ascorbic acid is preferentially toxic to tumor cells suggesting that it could be useful as a chemotherapeutic agent. While again I would not suggest using HDVC as a stand-alone treatment, studies have shown it to kill cancer cells, slow the growth of cancers, and greatly improve the effectiveness of other cancer treatments. Some research shows that HDVC can reduce tumor size and may lead to tumor regression, including in patients with metastatic disease.

 Antioxidant vs Pro-oxidant

At ordinary doses, vitamin C acts as an antioxidant, protecting cells from free radical damage. However, at high doses, it acts like a pro-oxidant drug that produces hydrogen peroxide, which targets cancer cells while leaving normal cells unharmed. Hydrogen peroxide is lethal to cancer cells. It oxidizes the tissues by converting the free radicals into hydrogen peroxide that can destroy the cancer cells and inhibit their energy supply.

According to Dr Steve Hickey, PhD, ” Fortunately within tumors, vitamin C and certain other dietary ‘antioxidants’ act as oxidants, rather than antioxidants.  Morever, the same substances act as antioxidants within healthy cells.  This means they can destroy cancer cells, while simultaneously improving the health of the rest of the body.”

According to the National Institute of Health:

“Many laboratory studies have been done to find out how high-dose vitamin C may cause the death of cancer cells. The anticancer effect of vitamin C in different types of cancer cells involves a chemical reaction that makes hydrogen peroxide, which may kill cancer cells.”

Vitamin C also does more than just kill cancer cells. It boosts immunity which we know is essential for the prevention and management of cancer.

Vitamin C, Immunity, and Cancer: 

  • Increased immune function with enhanced antibody production (lymphocytes)
  • Stimulation of collagen formation necessary to wall off tumors (replacement and destruction of tumor cells)
  • Enhanced natural killer cell activity
  • Inhibits of hyaluronidase to keep ground substance intact and preventing metastases
  • Inhibition of oncogenic viruses
  • Supports the p53 tumor suppressor gene
  • Corrections of C deficiency commonly seen in cancer patients
  • Enhanced healing of surgical wounds
  • Enhanced anticancer effects of certain chemotherapeutic agents
  • Chemotherapy and radiation better tolerated when HDVC is used (including reduced pain)
  • Combining high dose vitamin C with radiation and/or certain types of chemo may be more effective than these treatments on their own
  • Prevents free radical damage by responding to inflammation and its resulting oxidative stress
  • Produces hydrogen peroxide which may help to kill cancer cells by forming the hydroxyl radical in cancer cells because they lack catalase
  • May help to neutralize certain cancer producing substances

There is a plethora of research beyond the early studies done by Pauling and Cameron.  For example, Drs. Murata and Morishige of Saga University in Japan showed that cancer patients given 5–30g of vitamin C lived six times longer than those on 4g or less, while those suffering from cancer of the uterus lived 15 times longer on vitamin C therapy. This was also confirmed by the late Dr Abram Hoffer in Canada, who found that patients on high doses of vitamin C survived, on average, ten times longer.

Treatment with high-dose vitamin C has been found to slow the growth and spread of prostate, breast, pancreatic, liver, colon, malignant mesothelioma, neuroblastoma, and other types of cancers.

Oral Vitamin C is better Than Intravenous Vitamin C

However through the work of Hickey, and others, we have learned that not only can oral intake be as effective asintravenousous C, it can actually be even more effective. Hickey maintains that since you can take oral vitamin C throughout the day as well as daily, the treatment is more effective.

He says that “the ‘vitamin C as chemotherapy’ model used for IVC assumes delivery of a relatively short, high burst of ascorbate. However, this does not apply to oral doses, which can be used to produce long term, sustained plasma levels.”  His findings show a large increase in cancer toxicity when the experimental exposure time was increased from 1 hour to 24 hours. He also found that alpha alpha-lipoic acid (R-ALA), copper, selenium, and other redox (oxygen –reducing) active supplements greatly increase the selective cytotoxicity of ascorbate.”

You may find the full article informative: Vitamin C and Cancer: Is There a Use for Oral C

The trick to being able to consume high levels of oral C without the typical bowel intolerance is to use Liposomal C or  Sodium Ascorbate. My two favorite brands of liposomal C are Mercola  and  Lypo-Spheric .  You can also make it at home.  One trip to google will provide DIY methods.

The Role of Sodium Ascorbate  

While liposomal C has been used for many years, new research has found that another form of vitamin C, sodium Ascorbate, is highly effective as  is also more affordable.

Please view this extremely informative video by  Dr Suzanne Humphries.  You will learn the safety and health benefits of  high dose vitamin C. She includes considerable information as to why sodium ascorbate can be helpful in your protocol.

 

How to Use HDVC

It is important to work with a professional before beginning this treatment.

  • A  G6PD test is recommended before any IVC infusions are given. Patients with a rare inherited disorder called G-6-PD deficiency should not be given high doses of vitamin C, due to the risk of hemolysis (a condition in which red blood cells are destroyed). Patients with a history of kidney disorders should not be treated with HDVC unless at the advice of a qualified physician (and supplementation with B6 as well as magnesium).
  • It is best to start slowly. Practitioners typically start a patient with 10 or 20 grams, increasing over a period of time to 50 grams. In previous years the doses went as high as 100 grams, but more recent research indicates this is not necessary. For oral C, you may want to start out with small doses, starting at 1-2 grams, three times a day and build up to your optimal dose which could be anywhere from 4-20 grams.
  • The use of ascorbic acid urine strips is recommended to find the right dose you’re your individual needs.
  • Consider supportive supplements such as alpha alpha-lipoic acid (R-ALA) and selenium.
  • You may feel ‘wiped out’, foggy, or shaky when you first begin this treatment. Plan accordingly. If using IVC, be sure you have someone to escort you home. If starting at home, plan to take a restorative nap. Consuming calcium/magnesium rick foods during this therapy can help alleviate such symptoms.
  • Do not use IV Glutathione the same day as HDVC as they will cancel each other out (antioxidant and proxidant).
  • Never begin any new therapy without the advice of a qualified physician

For more information and resources:

https://www.csom.ca/wp-content/uploads/2013/03/Vitamin-C-and-Cancer-Is-There-A-Use-For-Oral-Vitamin-C-28.1.pdf  Steve Hickey, PhD and Hilary Roberts, PhD

http://www.peakenergy.com/news/VitaminC_Cancer_w_Comments.pdf

http://www.ncbi.nlm.nih.gov/pubmed/9630735

https://www.youtube.com/watch?v=y0LLX0sgwAU

http://www.cancer.gov/about-cancer/treatment/cam/patient/vitamin-c-pdq#link/_5

http://healthycures.org/high-dose-vitamin-c-injections-shown-annihilate-cancer

http://drsuzanne.net/dr-suzanne-humphries-oral-intravenous-vitamin-c/

http://www.healingcancernaturally.com/vitamin-c-cancer-therapy-cure.html

https://www.cancertutor.com/vitaminc_ivc/

http://www.doctoryourself.com/riordan1.html

You may also want to visit the website of the Vitamin C Foundation at: http://vitamincfoundation.org/alerts.php

Elyn
~~If you don’t know your options, you don’t have any~~
Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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Low Dose Naltrexone: The Affordable Non-Toxic Cancer Therapy Your Doctor is NOT Telling You About

In Alternative Cancer Therapies, Breast Cancer, Healing Cancer Naturally, Uncategorized on July 27, 2016 at 7:43 am

Naltrexone has been traditionally used to help drug and alcohol abusers.  But did you know that at very low doses, Naltrexone is a highly effective off-label therapy for cancer?

I rarely advocate for the use the pharmaceutical drugs, but low dose naltrexone (LDN) holds so much promise for those with cancer, that it virtues need to become known.

Naltrexone was approved by the FDA decades ago for opiate and alcohol dependence. And although the “off-label use” of a drug—prescribing it to treat conditions other than those for which it is approved—is perfectly legal, almost all doctors fail to do this. Sadly, most doctors refuse to consider any and all effective therapies that fall outside the mainstream. But this is a terrible disservice to those with cancer!

So why aren’t doctors prescribing it?  It comes down to money and ignorance.  In this case, the drug is cheap and the patent for naltrexone expired. Therefore there is no financial incentive for the drug company to advertise or push doctors to recommend it. Plus, or because of this and the resulting ignorance, many doctors take the stance that “if it were that good I would know about it”.

However, through the work of prominent doctors and researchers such as Dr Bernard Bihari MD, Dr Burt Berkson MD, and others, more and more researchers and patients are taking notice—and I suggest you do too!

The Birth of LDN as a Promising Therapy

Dr Bihari first started using naltrexone for his patients with addiction problems. He found that it worked well by attaching to the opioid receptors in the brain that heroin and other opiate drugs seek out.  In doing so, it blocks these receptors effectively preventing the ‘high’ that these drugs offer. However, during this time he found that naltrexone also blocked the binding of the body’s own endorphins and natural opiates that boost mood and sense of well-being. Thus, his patients felt terrible, so he stopped using the naltrexone.

However, through his work on AIDS Bihari found that at low doses given at bedtime, naltrexone stimulated endorphin release.  He found that endorphin levels doubled and often tripled which jumpstarted his patient’s immune systems— and the patients got better.

According to Dr Bihari, endorphins play a central role in immune function, and LDN enhances the immune response by stimulating endorphin production.

With this new development he began to focus on the immune system as a healing tool.  He found that LDN worked for other diseases linked to immune dysfunction such as MS — and cancer as well.

 How LDN Works

LDN revisedLDN works by blocking opioid receptors, which in turn helps activate the body’s immune system. It seems that when LDN is taken at bedtime, it binds to opioid receptors and temporarily blocks endorphins from attaching. This signals the body to increase endorphin production. The result is a dramatic boost in immune function. Then the opiates bind to receptors in bone marrow stem cells, macrophages, natural killer cells, T and B cells, and other immune cells and influence their development, differentiation, and function.

In other words, opioid receptors aren’t exclusive to the brain. They’re also present on all types of immune cells, including macrophages, natural killer cells, T- and B-cells, and even stem cells. As a result, the flood of endorphins set into motion by LDN stimulates the immune system and enhances the body’s ability to fight disease.

LDN upregulates opioid receptors in cancer cells, stimulating the process of programmed cell death (apoptosis) — thus killing some of the cancer cells.  It also stimulates certain immune cells that tend to go after cancer cells, including T4 and natural killer cells (NK cells).

Recent research also suggests that natural opiates also bind to receptors on cancer cells and inhibit their growth. LDN has been found to shrink tumors and inhibit their growth.

Major institutions such as The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have done considerable research on LDN.  Numerous case studies have shown it is effective for a variety of cancer types, including colon, prostate, melanoma, multiple myeloma, breast, ovary, uterine, brain, neuroblastoma, lung, Hodgkin’s disease, non-Hodgkin’s lymphoma, and chronic lymphocytic leukemia.

ALA and LDN, a Powerful Combination

There is also a combination therapy called the Berkson Method – using Alpha-Lipoic Acid alongside LDN. Lipoic acid is a potent antioxidant that neutralizes free radicals and generates and increases levels of vitamins C and E as well as CoQ10 and glutathione. Moreover, ALA is a modifier of gene expression. It seems to interfere with some of the genes that promote cancer. Note: look for R-ALA as it is the form found naturally occurring in the body and is the biologically active form of alpha lipoic acid. S-ALA is synthetic and should not be used.

Can I take LDN If I take Tamoxifen or Aromatase Inhibitors?

Several of my clients voiced their concerns about compatibility with aromatase inhibitors or tamoxifen. There are few reports of LDN interactions with other medications (do not use with opiate painkillers). Specifically though, according to Integrative Pharmacist David Restrepo, RPh (Vitahealth Apothecaries, New York), this should not be a problem with hormone therapies:

There is no data that suggests using AI’s, (regardless of the generation i.e. 1st 2nd or 3rd) and LDN cause any drug interaction. It’s important to keep a few things in mind.

Firstly, the normal dose of naltrexone is anywhere from 50-300mg daily and used as an opiate antagonist. Using this high of a dose would make there be a better chance of experiencing “side effects” but again, no drug interaction with AI’s. Secondly, naltrexone is selective to opiate receptors where AI’s are selective estrogen receptor modulators.

Lastly, they both are metabolized by the liver, BUT naltrexone, at such a low dose, is effective because it causes a “spike” in the bloodstream, where AI’s stay in the bloodstream much longer because of their relatively longer half-life. Any person worried about the possibility of drug interactions can just take their AI in the morning and the LDN AT NIGHT which is when it works best anyway. David Restrepo, RPh

What If I have Hashimoto’s, Graves or Another Autoimmune Disease?

One should always consult with a qualified doctor before taking any medication, but some people can actually achieve remission from autoimmune diseases by using LDN.  This is because LDN modulates the immune system.  It lowers inflammation as well as the immune reaction. However, if you have thyroid issues or any type of autoimmune disease, your doctor will likely start you out at a lower than normal dose.

Is LDN a Cure?

I’m not suggesting that LDN is a the magical cure for cancer, and in fact, it is not actually ‘curative’. This is partly because, like chemo and radiation,  it does not resolve the reason for the cancer.  But it is also is important to understand that LDN is a cell growth regulator. The goal is to regulate these cells and slow down the proliferation. Taken continuously, countless patients have achieved and maintained remission. Thus, in some cases,with the use of LDN cancer can be treated as a manageable chronic disease without the damaging effects of conventional chemotherapy and radiation–which on their own are rarely curative.

Therefore, I do recommend that you look into this safe, inexpensive ($25–30 a month) therapy. It may take some work convincing your doctor to write the script as this is an “off-label” use of an approved drug—but its long track record of efficacy makes it worth the effort. If you need some assistance with finding a doctor who will write the script, respond below in the comment field.

LDN requires a prescription and at is only available at compounding pharmacies. LDN must not be a timed-released preparation and should be taken at bedtime. The therapeutic dose ranges from 1.5-4.5mg, the later being the typical dose. Some people find that they have trouble sleeping or experience vivid dreams the first week taking LDN.  This issue should subside but consult with your doctor as he or she may want to reduce your dose for a week or so. If you have trouble filling your script, contact Vitahealth apothecary. www.vitahealthrx.com.

If you need something to back up your request to your doctor or just for more information, visit www.lowdosenaltrexone.org  to learn more as well as to find thousands of inspiring healing stories.

Again, I am not suggesting that LDN is the magical ‘cure-all’ for cancer, but it does offer a safe and inexpensive alternative to toxic cancer therapies. You might have to find an ‘outside the box’ doctor to prescribe this off-label drug, but it may well be worth the effort. If you would like to discuss how to incorporate LDN into your protocol, please contact me.

Lastly, this is something I have added to my own protocol. After all, who couldn’t use a few more  ‘feel good’ endorphins. For more of my story, please click here. It is not complete as far as supplements go, but that list is long.

 This information is for educational purposes only. It is not intended to treat, cure, prevent or diagnose any diseases or conditions. The information in this post does not represent medical advice, and I encourage you to discuss this information with your integrative oncologist or naturopathic doctor. Always consult with a medical doctor before you consider any prescription or over the counter drug or herb.

Read 12 Things a Cancer Doctor Should Never Say, my most recent article on The Truth About Cancer Website.

Elyn
~~If you don’t know your options, you don’t have any~~
Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She brings a plethora of knowledge to her practice and will help you think outside the box so you can incorporate every lifeline you may need for long term survival. Elyn is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. She is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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