elynjacobs

Archive for the ‘Estrogen and Breast Cancer’ Category

Could the Natural Alternative to Tamoxifen and Aromatase Inhibitors be in Your Refrigerator? Part II

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Alternatives to Anti-Hormone Therapy For Breast Cancer, Alternatives to Hormone Therapy for Breast Cancer, Alternatives to Tamoxifen, Anticancer foods, foods for colon cancer, foods for breast cancer, antioxidants, aromatase inhibitors, BPA and breast cancer, Breast Cancer, Cancer, Cancer Coach, cancer stem cells and recurrence, Estrogen, Estrogen and Breast Cancer, Natural Aromatase Inhibitors, prostate cancer, SERMS, Tamoxifen, Uncategorized on November 15, 2019 at 9:07 am

Synthetic selective estrogen receptor modulators (SERMS) such as tamoxifen and pharmaceutical aromatase inhibitors are often recommended for ER+ breast and other hormone-driven cancers, but they have significant adverse effects. Is it possible that natural plant products can perform the same function without the risks and damage of pharmaceuticals? Research says they can.

While estrogen plays many important beneficial roles in humans, the proliferation of ER+ breast cancer cells can sometimes be enhanced by estrogen (especially in the absence of progesterone), which may induce multiple processes involved in cell survival and cell cycle progression. Beyond the estrogen dominance that comes from a lack of progesterone, it is not necessarily our own estrogen at fault, but more likely xenoestrogens — the chemical estrogens, environmental hazards such as BPA and BPS — Bisphenol A and S.

However, to add clarity to the estrogen equation that oncologists speak of, the body has two different estrogen receptors, ERα (alpha) and ERβ (beta). ERα has a proliferative effect, and ERβ acts as a negative regulator of ERα in breast cancer cells, counteracting the proliferative effect of estrogens. Importantly, plant estrogens (phytoestrogens) preferentially interact with ERβ and display high specificity toward ERβ transactivation. Phytoestrogens, also known as phytochemicals, are synthesized from plants and vegetables. They show low estrogenic activity or anti-estrogenic activity with anti-proliferative effects that studies show offer nutraceutical alternatives to pharmaceutical anti-hormone therapies for various cancers.[ii]

For the men reading this article (including those with breast cancer), androgens and estrogens also influence the development and progression of prostate cancer. Research shows that phytoestrogens such as soy could be used alone or in conjunction with anti-hormone therapies for prostate cancer to target metabolic pathways involved in androgen and estrogen syntheses and epigenetic modifications of DNA to promote tumor-suppressor genes.[iv]

In a nutshell, phytoestrogens may be useful as substitutes for breast cancer treatments such as tamoxifen or aromatase inhibitors, and could be extremely helpful for other hormone-related cancers.

The Role of Phytoestrogens as Replacements for SERMs and Aromatase Inhibitors

It is well-established that many foods and natural products have beneficial effects on ER+ breast cancer as well as other hormone-driven cancers.  Pytoestrogens are structurally similar to our own estrogen, but functionally are weakly estrogenic (weakly mimicking estrogen) or antiestrogenic (blocking estrogens’ effects). They have been researched extensively for their role in the interaction with estrogen receptors. The beauty is that they block the receptors from more volatile estrogens.  As such, they deserve consideration in preventive and therapeutic settings for the intervention of cancer initiation and progression.

Studies show that phytoestrogens may provide an alternative or complementary approach to anti-hormone treatments. For example, 2017 research published in the International Journal of Molecular Sciences cited many studies confirming that an important application of phytoestrogens is that they could be used as an alternative to the SERMs.[iii] In general, phytoestrogens act as aromatase inhibitors by decreasing aromatase gene expression and inhibiting the aromatase enzyme.   

Some of the more powerful phytoestrogens include flax and sesame seeds as well as whole soy. 

Flax and sesame seeds have anticancer, breast tumor-reducing effects. Both lignans are metabolized to estrogen-like enterodiol and enterolactone, and reduce cell proliferation and apoptosis.[xiv] While each works a bit differently, both may be useful as an effective adjuvant therapeutic agent against tumor development and progression, and therefore, could be used in the prevention and/or treatment of various types of cancer. Studies show that higher intakes of lignans such as flax and sesame seeds are associated with a reduced risk of breast cancer. Flax seed works with tamoxifen to inhibit breast cancer tumor growth, so if you choose to take tamoxifen, know that you can also benefit from flax.  

I have written extensively on the benefits of flax seed, but to recap, a few of the benefits of flax are the following:

  • Decreases cell proliferation rates and inhibits tumor growth in ER+ cancers
  • Decreases angiogenesis (blood supply for tumors) and increases apoptosis (cancer cell death)
  • Influences ER-negative and ER-positive tumors by decreasing insulin-like growth factor-1 (IGF-1), epidermal growth factor receptor (EGFR), HER2 and the vascular endothelial growth factor (VEGF) which supports angiogenesis
  • Reduces growth and metastasis of ER-negative and triple negative breast cancers
  • Favorably influences tumor suppressor genes

For more on flax seed and breast cancer, please read some of my other posts, such as  Demystifying Flaxseed and Estrogen and Flaxseed, Better Than Tamoxifen for Breast Cancer.

Soy: Numerous studies indicate that genistein, the most abundant isoflavone present in soybeans, has anti-proliferative effects on various cancer cells, including prostate, ovarian, and breast. Like other phytoestrogens, genistein interferes with the effects of estradiol by binding to estrogen receptors. This is good as soy may also inhibit inflammation and boost anticancer immune responses, while other estrogens do not. The following are a few key findings of soy[v]:

  • Inhibits NF-kB activity in prostate, breast, lung, and pancreatic cancer cells. Nf-kB plays a crucial role in immune response, inflammation, cell growth and survival.
  • Selective tyrosine kinase inhibitor impeding angiogenesis, a major factor in cancer growth and proliferation. Tyrosine kinases play important roles in cell proliferation, survival, migration and differentiation are often altered in cancer cells, leading to malignancy
  • Induces cancer cell death (apoptosis) in several cancer cell lines, including prostate, ovarian, and breast cancer
  • Modulates EGF (epidermal growth factor) which has been implicated in the development and growth of many types of cancer cells
  • Long-term consumption seems to result in a decreased response to stimulation by estradiol[vi]

Please note that soy consumption is somewhat controversial. Please work with your coach or medical professional to see if soy consumption is right for you.

More Notable Phytoestrogens                                                                            parsley root

  • Apigenin is a natural flavonoid commonly found in fruits and vegetables such as parsley, celery, thyme, chamomile tea, and oranges. The chemical structure of apigenin is similar to estrogen and as such it mimics estrogen. 2107 research indicates that phytoestrogens such as apigenin and resveratrol have the therapeutic potential act like SERMs and could be considered in the development of therapeutics for breast cancer and brain disease.[vii] Extensive studies show that apigenin has potent antioxidant and anticancer activities in ER-positive and ER-negative breast cancer. Apigenin also inhibits proteasome, which certain cancer cells need for survival. By inhibiting proteasome, phytoestrogens such as apigenin induce apoptosis in prostate, breast, and many other cancer cell lines.[viii]
  • Pau d’ Arco exhibits selective anti-proliferative effects in carcinoma cell lines. A study performed at the Strang Cancer Prevention Center in New York found that the anti-proliferative effects of herbal medicines such as pau d’arco may correlate with down-regulated estrogen responsive genes and up-regulated apoptosis-specific genes. The researchers believe their data validates the need to prioritize efficacious herbal medicines and concluded that phytoestrogens such as pau d’arco may provide an alternative or complementary approach to endocrine therapy for breast cancer.[ix] Read more
  • Broccoli: The sulforaphane in broccoli (particularly in broccoli seeds and sprouts) has been found to inhibit proliferation and down-regulates hormone receptor expression in MCF-7 cells. Sulforaphane also passes the blood brain barrier and targets cancer stem cells. If you cannot find sprouts locally, I recommend a supplement.sprouts
  • Luteolin and Naringenin: Flavonoids, especially flavones such as luteolin and flavanones such as naringenin are potent aromatase inhibitors. [x] Luteolin has also been found to down-regulate aromatase gene expression. Luteolin is found in celery, thyme and chamomile tea. Some rich sources of naringenin include bergamot, grapefruit, tomatoes, and tart cherries.
  • Quercetin, found in abundance in food sources such as apples, onions, tea, and red wine, has been reported to have strong antioxidant, anti-inflammatory, antiviral, and anticancer effects. It has the ability bind at high affinity to estrogen receptors, resulting in inhibition of estrogen-regulated cell growth and proliferation[xi]
  • Hesperetin, found in citrus fruits and essentials oils, exerts it anticancer actions by inhibiting cell proliferation, inducing apoptosis, and by regulating aromatase activity and oxidative stress. Although hesperetin is unable to bind to ERs, it is effective in inhibiting cell proliferation of ER+ breast cancer and dramatically decreasing tumor size and other actions. Hesperetin has also been found to reduce serum estrogen levels and down-regulate estrogen target genes and estrogen metabolism-related genes.[xii]. Try putting a drop or two of lemon essential oil in your water, or grating the peel of an organic lemon.
  • Black seed contains thymoquinone, a phytochemical compound found in plant Nigella sativa. It has been found to initiate apoptosis, improve estrogen metabolism, and regulate signally pathways in breast cancer.
  • Vitamin E inhibits cell proliferation, down-regulates the expression of ERα, ERβ, COX-2, and serum estrogen levels (should always be mixed tocopherols, not just d-alpha.
  • Red Clover binds to estrogen receptors, inhibits cell proliferation, and initiates apoptosis in ER+ breast cancer cells.
  • Ellagic acid, a dietary flavonoid present in berries, grapes, pomegranates, and nuts, inhibits cell proliferation and promotes apoptosis in ER+ breast cancer cells.
  • Eugenol, a compound found in clove oil, inhibits cell proliferation and initiates cancer cell death in both ER+ and ER- breast cancers. Excitingly, one study done in Indonesia found that eugenol  is a potent ERa antagonist. The researchers indicate that not only does it work just like tamoxifen, but it may actually work even better.
  • This list is  not inclusive: There are many more powerful phytoestrogens. For more cancer-fighting alternatives to pharmaceuticals, please read my articles on Natural Alternatives to Aromatase Inhibitors and Natural Alternatives to Tamoxifen.

Phytoestrogens can be our friends, but know that herbs are powerful. I have no concerns with food-based phytos, but do take care with extracts. They are best rotated so as to maximize benefits, reduce the chances of resistance, and avoid interactions. Drugs, of course, are often even more dangerous, yet are routinely prescribed.

                               Trust me, I’m a doctor” Peter Gøtsche

I interviewed Peter Gøtsche, author of Deadly Medicines and Organised Crime, on my radio show a few years back. Amazing man, whose controversial views have since gotten him tossed from the Cochrane Collaboration, which he co-founded. Sadly, there are many who wish to silence the voices who speak against Big Pharma.

Like me, Gøtsche worries that most people let their doctors make the decisions for them, but the evidence tells us that we should be cautious. He is a strong advocate for the avoidance of drugs and while not against medical interventions, believes one can not just blindly follow the orders of the medical community.

Notably, there is tremendous variability in the metabolic processing of phytoestrogens and pharmacological drugs, thus establishing the difficulty and complexity of this topic. The bottom line is that it extremely important that one understand that it may not make logical sense to attempt to poison one’s way back to health. Certainly drug therapies have worked for many. That said, NO ONE was every born tamoxifen or AI deficient, but over time we may become estrogen dominant, increasing our risk for cancer. It behooves us all to do our research and decide for ourselves whether drugs or holistic remedies are best, or even a combination of both.  

Estrogen plays many important roles in humans, so it may not make sense to arbitrarily take it away. If you are estrogen dominant (meaning out of balance with progesterone), you may want to consider a bio-identical progesterone cream (I like that one as it is paraben-free, soy-free, and Non GMO).

Read Part I of this article HERE.

Reminder: To get an additional $30 off on the online course for breast cancer,  Toxic Free Me, enroll now and use this LINK. This course will further delve into alternatives for anti-hormonal therapies.

An online course not right for you? Know that I am always there for individual consultations.  To inquire about a consult, please visit me HERE.

Life is a journey, just be sure that journey is on-course for a healthy life.

In your everlasting good health,

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150res for PrueElyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make healthier, less-toxic choices for their healing. She emphasizes the importance of not just surviving cancer, but surviving well and reducing the risk of recurrence. She is a Contributing Editor for The Truth About Cancer and is on the Medical Advisory Board for BeatCancer.Org and the Advisory Board to the Radical Remission Project. Elyn has written for numerous journals and publications. She was the former Executive Director of the Emerald Heart Cancer Foundation and the creator and host of the Survive and Live Well Radio Show. To contact Elyn, visit www.elynjacobs.com. Elyn offers consults via Skype, phone, or in-person. Elyn does not provide online advice.

DISCLAIMER:
Elyn Jacobs does not provide medical advice. The information provided is for general information only. No online site should be used as a substitute for personal medical attention.

This information is for educational purposes only and is not a recommendation to forgo medical advice and treatment.  This post is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist. The information provided is from my research and not to be taken as scientific evidence.

Affiliate Links Disclosure:

Some product links on some posts are affiliate links. This website is monetized in part through the use of affiliate links. This means that if you were to click on a link that is an affiliate link and purchase an item after clicking on that link, I may receive a small percentage of the sales price. I only recommend products that I love and use often. Thank you for your support!

Follow Elyn on Facebook

Follow Elyn on LinkedIn

[i] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535874/; Notably, there are numerous  crsos-references cited in this article that support the use of phytoestogens as nutraceutical anti-hormone therapies for various cancers.

[ii] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535874/

[iii] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535874/; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699002/

[iv] https://www.ncbi.nlm.nih.gov/pubmed/27194038; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535874

[v] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535874/#B61-ijms-18-01381; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535874/

[vi] https://www.ncbi.nlm.nih.gov/pubmed/8625449

[vii] https://www.ncbi.nlm.nih.gov/pubmed/28396216; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033666/

[viii] https://www.ncbi.nlm.nih.gov/pubmed/26771497; https://www.ncbi.nlm.nih.gov/pubmed/25408199

[ix] https://www.ncbi.nlm.nih.gov/pubmed/19578798

[x] https://www.ncbi.nlm.nih.gov/pubmed/21741436

[xi] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203161/#b9

[xii] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535874

[xiii] https://www.ncbi.nlm.nih.gov/pubmed/26614455

[xiv] https://elynjacobs.com/2016/02/28/flaxseed-better-than-tamoxifen-for-breast-cancer/; https://www.ncbi.nlm.nih.gov/pubmed/29032105; https://www.ncbi.nlm.nih.gov/pubmed/22136581

 

Could the Natural Alternative to Tamoxifen and Aromatase Inhibitors be in Your Refrigerator? Part I

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Alternatives to Anti-Hormone Therapy For Breast Cancer, Alternatives to Hormone Therapy for Breast Cancer, Alternatives to Tamoxifen, Anticancer foods, foods for colon cancer, foods for breast cancer, aromatase inhibitors, Breast Cancer, Cancer, Cancer Coach, Emotional Healing, Estrogen, Estrogen and Breast Cancer, Uncategorized on November 14, 2019 at 9:59 am

Estrogen play an important role in overall health in humans—it protects your heart, lungs, eyes, brain, bones, skin, and hair, averts cognitive decline, and does so much more. Estrogen is also protective against adverse symptoms during the peri-and postmenopausal periods. But estrogens are known to stimulate cellular proliferation associated with certain cancers. Hence, if you have been diagnosed with a hormone-related cancer, your doctor may advise a synthetic selective estrogen receptor modulator (SERM) such as tamoxifen or a pharmaceutical aromatase inhibitor such as Femara (letrozole), Arimidex (anastrozole), or Aromasin (exemestane).

Of course, these pharmaceutical drugs come with a host of detrimental side effects. What’s a person to do?

Side Effects and Resulting Effects of Pharmaceutical Anti-Hormone Drugs

pills tamoxifenSome side effects of tamoxifen include severe muscle pain, weight gain, thickening of endometrial lining of the uterus, daytime sleepiness, nausea, edema, hot flashes, vaginal hemorrhage, increased risk of cataracts, acute glaucoma, and other eye issues. It is not recommended to take tamoxifen if you have impaired CYP2D6 enzyme, nor should you take medications that block the activity of CYP2D6, such as Benadryl, Prozac, Paxil, and Zoloft (these lists are not inclusive) during treatment. Tamoxifen has been declared a human carcinogen by the WHO, NIH and other authorities.

Side effects of aromatase inhibitors include damage to the heart, never-ending flu-like symptoms, hair thinning and loss, joint pain, stiffness and swelling, hot flashes, vaginal dryness, and headaches, a feeling of tiredness and lethargy, difficulty breathing, nails breaking down and peeling, memory fog, depression and mood swings, balance problems, sleep disorders, tightness of the chest, bone thinning, and more.

In the summer edition of Cure magazine, they spoke of a doctor who when asked why he didn’t tell his patient about the side effects of the prescribed hormonal therapy, replied “some women would not take the pill if they knew bout the side effects”. Incidentally, these were not listed on the medical paper that came with her bill.

Clinical trials have indicated that resistance develops with both tamoxifen and aromatase inhibitors. This is another major pharmaceutical problem and cause of serious concern to clinicians and patients.

So, again what exactly is a person to do?

The easiest and most logical answer is to eat copious amounts of phytoestrogens throughout the day.

Phytoestrogens are plant-derived naturally occurring compounds that have chemical structures similar to estrogens. Phytoestrogens have been found to decrease cancer risk by inhibiting aromatase activity and CYP19 gene expression (The aromatase enzyme is a product of the CYP19A1 gene).

Aromatase plays an important role in breast cancer as it converts androgens to estrogens in many human tissues, the result of which has been known to stimulate cellular proliferation in certain cancers. In the vast majority of breast cancers, estrogen levels play a role tumor growth and depend on the activity of CYP19.

Research performed in 2015 by the Department of Physiology and Developmental Biology and The Neuroscience Center at Brigham Young University, indicates that phytoestrogens act as aromatase inhibitors by decreasing aromatase gene expression and inhibiting the aromatase enzyme. Their findings emphasize that estrogens have a significant impact on health and that phytoestrogens (being of similar structure to 17β-estradiol) have strong potential as anticancer agents.[i]

The researchers concluded that phytoestrogens not only act as SERMs (as has been previously reported and I will get into in Part II of this post), but also have the ability to alter the activity of the aromatase enzyme. They go on to remind us that the inhibition of aromatase activity and gene expression represents a key mechanism of how phytoestrogens may contribute to decreased cancer risk and recurrence.

The important difference is that phytoestrogens do not initiate the cascade of negative effects of pharmaceutical drugs and as estrogen modulators, may stave off the negative effects of declining estrogen, making them effective in more ways than one. Further, unlike drugs, they offer significant cancer-fighting abilities. For example, the apigenin in parsley is known not only for its aromatase-inhibiting abilities, but also for promoting cancer cell death, including cancer stem cells. parsley

In Part II of this post I will discuss many different phytoestrogens—all of which play a significant roll in the management of hormone-related cancers. In the meantime, a few of my favorites are flax and sesame seeds, broccoli sprouts, including the seeds (sulforaphane), parsley (apigenin), and organic whole soy.

However, as a strong reminder, estrogen is not the biggest driver of cancer, at least not your own estrogen. Emotional and environmental toxins (including xenoestrogens such as BPA and BPS) are often at the root of it all, as well as the viral factor—it is imperative that you resolve these issues as well as anything that may have contributed to your cancerous environment.

Importantly, it is not always wise or even necessary to reduce estrogen (many post-menopausal women already suffer from low estrogen). This is especially true for very thin women as post-menopause, estrogen is no longer made in the ovaries, but rather from adipose tissue (fat, especially in the breasts and belly), of which they may have very little. (This is also why many doctors advise their patients to lose weight, if necessary). Thin women might benefit more by raising progesterone. Reminder that you have to be very careful with compounded bio-identicals; read more HERE.

Many of my followers have been asking about a safe  bio-identical progesterone cream (It is paraben-free, soy-free, and Non GMO). 

Read Part II HERE

Below are just some of the articles I have written on natural alternatives to tamoxifen and aromatase inhibitors:

Why You May Want to Reconsider Estrogen-Blocking Aromatase Inhibitors and Tamoxifen

Natural Alternatives to Hormone Therapy for Breast Cancer

What to Do if You Have Low Estrogen Levels and Your Doctor Prescribes an Aromatase Inhibitor

Potential Therapeutic Effects of Phytochemicals and Medicinal Herbs for Cancer Prevention and Treatment

Managing Estrogen Naturally

Flaxseed, Better than Tamoxifen for Breast Cancer

Flaxseed, the Anticancer Power Seed

Alternatives to Aromatase Inhibitors

 

Reminder: To get an additional $30 off on Marnie Clarks’ online course for breast cancer,  Toxic Free Me, enroll now and use this LINK. This course will also delve into alternatives for anti-hormonal therapies.

An online course not right for you? Know that I am always there for individual consultations.  To inquire about a consult, please visit me HERE.

Life is a journey, just be sure that journey is on-course for a healthy life.

In your everlasting good health,

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150res for PrueElyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make healthier, less-toxic choices for their healing. She emphasizes the importance of not just surviving cancer, but surviving well and reducing the risk of recurrence. She is a Contributing Editor for The Truth About Cancer and is on the Medical Advisory Board for BeatCancer.Org and the Advisory Board to the Radical Remission Project. Elyn has written for numerous journals and publications. She was the former Executive Director of the Emerald Heart Cancer Foundation and the creator and host of the Survive and Live Well Radio Show. To contact Elyn, visit www.elynjacobs.com. Elyn offers consults via Skype, phone, or in-person. Elyn does not provide online advice.

DISCLAIMER:
Elyn Jacobs does not provide medical advice. The information provided is for general information only. No online site should be used as a substitute for personal medical attention.

This information is for educational purposes only and is not a recommendation to forgo medical advice and treatment.  This post is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist. The information provided is from my research and not to be taken as scientific evidence.

Affiliate Links Disclosure:

Some product links on some posts are affiliate links. This website is monetized in part through the use of affiliate links. This means that if you were to click on a link that is an affiliate link and purchase an item after clicking on that link, I may receive a small percentage of the sales price. I only recommend products that I love and use often. Thank you for your support!

Follow Elyn on Facebook

Follow Elyn on LinkedIn

 

[i] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699002/

Pau d’arco for Breast, Prostate, Colon, and Other Cancers

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Alternatives to Anti-Hormone Therapy For Breast Cancer, Alternatives to Hormone Therapy for Breast Cancer, Alternatives to Tamoxifen, antioxidants, Breast Cancer, Cancer, Cancer Coach, chemotherapy, CLA and Cancer, colon cancer, Epstein-Barr Virus, Estrogen, Estrogen and Breast Cancer, foods that target cancer stem cells, Healing Cancer Naturally, inflammation, prostate cancer, SERMS, supplements that target cancer stem cells, Tamoxifen, Uncategorized on November 1, 2019 at 8:56 am

Pau d’arco, also known as Taheebo, is extracted from the inner bark of several species of Tabebuia trees that grow in Central and South America. The medicinal uses of Pau d’arco (PDA) date back to 1873.  PDA has been used in South America to treat a wide range of conditions, including pain, ulcers, arthritis, fever, prostatitis, Candida, osteoarthritis, cough, influenza, herpes, diabetes, ulcers, warts, infections, allergies, and even cancer, particularly cancers of the breast, colon, lung, prostate, and malignant melanoma.

What the Docs Have to Say

Dr. James Duke of the National Institutes of Health (NIH) and Dr. Norman Fransworth of the University of Illinois have reported PDA contains active substances (such as β-lapachone and lapacho) found to be highly effective against various cancers. Dr Paulo Martin, a Brazilian medical researcher, reported that PDA has powerful antibiotic, virus and cancer-killing properties.[i] The late integrative oncologist Dr. Mitch Gaynor also used Pau d’arco with his cancer patients.

What the Studies Say

Scientists have discovered that compounds in PDA called naphthoquinones (mainly lapachol and beta-lapachone) are the reason for these impressive healing abilities. PDA also contains a significant amount of the antioxidant quercetin, which has been found to inhibit growth of cancer cells, including cancer stem cells. Some of the exciting cancer research on PDA:

  • Exhibits selective anti-proliferative effects in carcinoma cell lines, including ER+MCF-7 breast cancer cells[ii]
  • Inhibits the growth of estrogen receptor positive breast cancer cells and activates cancer-fighting genes[iii]
  • May block estrogen receptors [much like the SERM tamoxifen] as it is a powerful phytoestrogen [iv]
  • Effective against some bacteria, fungi, viruses (including Epstein Barr), and parasites that may be involved in cancerous processes
  • Induces cell death in prostate cancer lines[v]
  • Induces apoptosis independent of P53 expression; notably, over-expression of bcl2, a contributor for a number of cancers – including melanoma, breast, prostate, chronic lymphocytic leukemia, and lung cancer, does not appear to inhibit the  B-lapachone in PDA[vi]
  • Inhibits angiogenesis, the ability of tumors to make new blood vessels in prostate and other cancers[vii]
  • Suppresses the growth and angiogenesis of lung cancer[viii]
  • Inhibits the growth of cancer in a wide range of cancers, such as breast, prostate, cervical, liver, lung, and colon* (see Quercetin below)
  • Appears to increase the effectiveness of chemo and decreases side effects

Research also shows that the lapachol in PDA may have the ability to stimulate the production of red blood cells in bone marrow, which could be helpful for those with low red blood cell counts (RBC). Pau d’arco is also thought to eliminate toxins in the body and purify the blood.

Enjoy Pau d’arco tea, tincture or capsules. Another good tincture is Pau D’ Arco Plus, which also contains dandelion and red clover. Use of PDA during pregnancy is not advised. A potent herb, PDA should be cycled – meaning a few weeks on and then take a break for a few weeks – or swapped out for another cancer-fighting herb. This is especially important for those taking drugs or herbs that thin the blood or for Candida, as resistant strains of Candida can develop.

Please also read my related published articles:

*Potential Therapeutic Effects of Phytochemicals and Medicinal Herbs for Cancer Prevention and Treatment  Contains a discussion on the powerful anticancer effects of quercetin.

Etiology of Chronic Disease: A Discussion on Epstein-Barr Virus

Spotlight on CLA, a Cancer-Fighting Fatty Acid: CLA (Conjugated Linoleic Acid) is a fatty acid found in grass-fed meats and dairy products, but can also be taken in supplement form.  CLA suppresses the development of cancer at various levels. CLA has been shown to decrease skin, liver, and colon cancer. Activating protein-1 (AP-1) is one of the main promoters of colon and breast cancer, but it is blocked by CLA (licorice root and rosemary-fresh or essential oil also do this). Human abdominal, breast, and axillary fat have the ability to convert androgens into estrogens. Some studies show CLA helps rid the body of belly fat and may modulate immune and inflammatory responses.

To get an additional $30 off on the Online Course for Breast Cancer, Toxic Free Me, enroll now and use this LINK.

Additional Resources for this article:

In your good health,

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150res for PrueElyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make healthier, less-toxic choices for their healing. She emphasizes the importance of not just surviving cancer, but surviving well and reducing the risk of recurrence. She is a Contributing Editor for The Truth About Cancer and is on the Medical Advisory Board for BeatCancer.Org and the Advisory Board to the Radical Remission Project. Elyn has written for numerous journals and publications. She was the former Executive Director of the Emerald Heart Cancer Foundation and the creator and host of the Survive and Live Well Radio Show. To contact Elyn, visit www.elynjacobs.com. Elyn offers consults via Skype, phone, or in-person. Elyn does not provide online advice.

DISCLAIMER:
Elyn Jacobs does not provide medical advice. The information provided is for general information only. No online site should be used as a substitute for personal medical attention.

This information is for educational purposes only and is not a recommendation to forgo medical advice and treatment.  This post is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist. The information provided is from my research and not to be taken as scientific evidence.

Affiliate Links Disclosure:

Some product links on some posts are affiliate links. This website is monetized in part through the use of affiliate links. This means that if you were to click on a link that is an affiliate link and purchase an item after clicking on that link, I may receive a small percentage of the sales price. I only recommend products that I love and use often. Thank you for your support!

Follow Elyn on Facebook

Follow Elyn on LinkedIn

[i] https://books.google.com/books?id=RIydBQAAQBAJ&pg=PA120&lpg=PA120&dq=dr+norman+farnsworth+pau+d%27arco&source=bl&ots=ZqFrjj9sQr&sig=

[ii] https://www.ncbi.nlm.nih.gov/pubmed/19578798; https://www.ncbi.nlm.nih.gov/pubmed/25891355

[iii] https://www.ncbi.nlm.nih.gov/pubmed/19578798

[iv]  http://www.ndhealthfacts.org/wiki/Phytoestrogen

[v] https://cancerres.aacrjournals.org/content/55/17/3712.short; https://www.ncbi.nlm.nih.gov/pubmed/27048660; http://www.ucdenver.edu/academics/colleges/pharmacy/currentstudents/OnCampusPharmDStudents/ExperientialProgram/Documents/nutr_monographs/Monograph-pau_darco.pdf

[vi] https://cancerres.aacrjournals.org/content/55/17/3712.short

[vii] https://www.ncbi.nlm.nih.gov/pubmed/27048660

[viii] https://www.ncbi.nlm.nih.gov/pubmed/27048660

New Online Course for Breast Cancer: Toxic Free Me

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Alternatives to Anti-Hormone Therapy For Breast Cancer, Alternatives to Hormone Therapy for Breast Cancer, Alternatives to Tamoxifen, Anticancer foods, foods for colon cancer, foods for breast cancer, antioxidants, aromatase inhibitors, BPA and breast cancer, Breast Cancer, Cancer, Cancer Coach, chemo and cancer stem cells, chemotherapy, colon cancer, Estrogen, Estrogen and Breast Cancer, foods that target cancer stem cells, Healing Cancer Naturally, High Dose Vitamin C, Hormone Balance, inflammation, Inflammatory Breast Cancer, Iodine, Mind Body Therapies for Cancer, Natural Alternatives to Aromatase Inhibitors, prostate cancer, Radiation, radiation and cancer stem cells, Tamoxifen, targeting cancer stem cells, trapped emotions and cancer stem cells, Uncategorized, what causes cancer to spread on October 28, 2019 at 9:22 am

As a holistic cancer coach (and survivor of stage 3 hormone-positive breast cancer), I work with people with many different types of cancer. However, the majority come to me looking to avoid the dreaded tamoxifen, aromatase inhibitors, Herceptin, Lupron, and other drugs and treatments, such as chemo and radiation. And of course, everyone is looking to get through cancer with the least amount of collateral damage and to do what they can to reduce the risk of recurrence or further cancers–to survive and live well. I coach one-on-one, but also offer a plethora of information on my website. However, some people are looking for options other than individual coaching or DIY (do-it-yourself) healing.

About a year ago I decided I would offer a webinar course to cover these topics and more. However, as life and work got very busy, I put that on hold. Meanwhile, my colleague and friend, Marnie Clark is now offering a fantastic ‘how-to-get-through-breast-cancer-course. Toxic Free Me is a comprehensive online-course with multiple learning modules.

The beauty of the course is that you can learn at your own pace. Plus, she will be adding to the course as new information comes out, and subscribers will have full access at no additional charge. The course is valued at $295 and offered for a limited time at $179, but if you enroll now and use this LINK, you get the entire course for only $149, with a 30-day money back guarantee.

Is this course for you? Are you determined to survive your cancer and live well? Are you looking for safe, non-toxic remedies for your cancer (alongside or without conventional treatments) that will support your body, build your immune system, and lower your risk of recurrence? Have a look at the full course description HERE.

Remember, when you enroll now and use this LINK, you get the entire course for only $149.

This information is for educational and is not a recommendation to forgo medical advice and treatment.  This post is not intended to treat, cure, prevent, or diagnose any disease or condition. The information provided is from my research and not to be taken as scientific evidence.

In your good health,

Elyn

~~If you don’t know your options, you don’t have any~~

Marnie_homepageMarnie Clark is a breast cancer coach, and also a 15-year breast cancer survivor. Marnie has studied natural medicine for over 25 years and knew that in order for her own body to heal from breast cancer, it would require a blend of both conventional and natural medicine. She now teaches others going through breast cancer about the things in nature that help to make the body hostile terrain for cancer cells, as well as empowering clients with knowledge about the lifestyle alterations that are crucial to the healing process. Marnie draws from several decades of experience in the disciplines of massage therapy, natural healing and nutrition, aromatherapy and energy healing. Her website is https://MarnieClark.com.

ej portrait 150res for PrueElyn Jacobs is a 12-year breast cancer survivor and holistic cancer strategist who helps people make healthier, less-toxic choices for their healing. She emphasizes the importance of not just surviving cancer, but surviving well and reducing the risk of recurrence. She is a Contributing Editor for The Truth About Cancer and is on the Medical Advisory Board for BeatCancer.Org and the Advisory Board to the Radical Remission Project. Elyn has written for numerous journals and publications. She was the former Executive Director of the Emerald Heart Cancer Foundation and the creator and host of the Survive and Live Well Radio Show. To contact Elyn, visit www.elynjacobs.com. Elyn offers consults via Skype, phone, or in-person. Elyn does not provide online advice.

 DISCLAIMER:
Elyn Jacobs does not provide medical advice. The information provided is for general information only. No online site should be used as a substitute for personal medical attention.

This information is for educational purposes only and is not a recommendation to forgo medical advice and treatment.  This post is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist. The information provided is from my research and not to be taken as scientific evidence.

Affiliate Links Disclosure:

Some product links on some posts are affiliate links. This website is monetized in part through the use of affiliate links. This means that if you were to click on a link that is an affiliate link and purchase an item after clicking on that link, I may receive a small percentage of the sales price. I only recommend products that I love and use often. Thank you for your support!

Follow Elyn on Facebook

Follow Elyn on LinkedIn

 

Could Aromatase Inhibitors Actually Increase One’s Risk for Breast Cancer?

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Alternatives to Anti-Hormone Therapy For Breast Cancer, Alternatives to Hormone Therapy for Breast Cancer, Alternatives to Tamoxifen, aromatase inhibitors, Breast Cancer, Cancer, Estrogen, Estrogen and Breast Cancer, Hormone Balance, Hot Flashes and Night Sweats, Soy and Breast Cancer Risk, Uncategorized on October 21, 2019 at 4:05 pm

Most oncologists recommend estrogen blockers or aromatase inhibitors for those with hormone-sensitive cancers. However, new research shows that decreased estrogen levels can promote insulin resistance, which may actually increase the risk of cancer of the breast, endometrium, and ovaries. 

To recap from my previous post, What You Need to Know About Sugar and Breast Cancer, insulin resistance leads to increased insulin in the body. High insulin triggers breast cancer cells to divide and grow.

After menopause many women face a dramatic increase in insulin resistance (and start noticing belly fat that wasn’t there before). Declining estrogen is considered to be the reason.[i] If decreased estrogen promotes insulin resistance, could intentionally reducing estrogen increase one’s risk of breast cancer? Can aromatase inhibitors actually promote breast cancer? Research shows they just might.

Decreased Estrogen Levels Promote Insulin Resistance

Studies (both clinical and animal) have shown a strong correlation between circulating estrogen deficiency and insulin resistance. At Texas A&M, a team lead by Dr. Shaodong Guo identified that decreased serum estrogen levels promote insulin resistance and that even a slight decrease in circulatory estrogen levels is associated with resistance and may increase the risk of cancer of the breast, endometrium, and ovaries. The researchers found that “for premenopausal women, even a slight decrease in their circulatory estrogen levels associated with insulin resistance may increase the risk for cancers, particularly in the organs having high estrogen demand (breast, endometrium and ovary). On the other hand, postmenopausal state with profound estrogen deficiency confers high risk for cancers in different organs with either high or moderate estrogen demand.”[ii]

According to the Guo, the lead investigator for the Texas A&M study, estrogen deficiency or impaired estrogen signaling is associated with insulin resistance. “Studies have shown the reduction of estrogen in postmenopausal women accelerates the development of insulin resistance and Type 2 diabetes.” He further explains that estrogen replacement therapy in postmenopausal women can reduce insulin resistance. “Clinical trials of estrogen replacement therapy in postmenopausal women have demonstrated a lowered insulin resistance as well as reductions in plasma glucose levels.”

2015 research published in the Journal or Diabetes Research also concluded that the loss of circulating estrogen E2 and impairment of its cellular activity can lead to an abrupt reduction in metabolic rate and that E2 replacement is preventive. “It is very clear that E2 has tremendous potential as a therapeutic against diabetes and its associated complications, but it has to be administered in a safer form and personalized to individual needs”. [iii]  While the link between synthetic HRT (hormone replacement therapy) and breast cancer has been established and therefore may not be an option, it  just doesn’t make sense to intentionally lower our own already-declining natural estrogen.

Many women choose bio-identical hormones, but to be clear, bios are not ‘natural’, they are chemically constructed in a lab. According to Dr Mache Seibel, M.D., author of The Estrogen Window, you have to be careful with compounded bio-identicals. He says that studies show that despite the fact that the prescription may be filled correctly, typically progesterone tends to be 60-80% lower than ordered and estrogen 80-200% higher than ordered which can result in increased estrogen dominance and could raise your risk of hormone-driven cancer. He also points out the serious risks of declining estrogen, which include increasing your risk of heart disease by 30% and dementia 70%. 

Why You Need Estrogen 

We need estrogen for aiding in the prevention of heart disease and for strong, healthy bones. In fact, estrogen is essential to the health of all parts of your body, from your eyes to your heart to your brain to everywhere else.  Estrogen also improves body fat distribution and B-cell function, and reduces inflammation. And of course, estrogen increases insulin sensitivity (and thus is protective against diabetes and metabolic syndrome predisposing one to obesity) and conversely, low estrogen levels can lead to increased insulin resistance or impaired insulin activity.

Given that studies show that the reduction of estrogen in postmenopausal women accelerates the development of insulin resistance and thus could promote breast cancer, it is hard to believe that aromatase inhibitors are always a good idea. Perhaps ‘prescribing’ phytoestrogens such as flax and sesame seeds, herbs, and even perhaps whole soy, would be a better tactic. Phytoestrogens are plant-based weak estrogens which bind to estrogen receptors in the body (just like tamoxifen) and through competitive inhibition, can prevent the receptor-binding of more potent estrogens (including xenoestrogen such as BPA). Phytoestrogens also promote hormone balance and homeostasis. One can also take steps to raise progesterone to balance natural estrogens by taking supplements such as zinc and vitamin E, lowering stress, and using an over-the-counter progesterone cream. I will further address the role of phytoestrogens and hormone-driven cancers in my next post.

Natural Aromatase Inhibitors

Some natural substances and formulas that reduce aromatase activity (should you need to reduce aromatase activity or improve estrogen metabolism or hormone balance) include Calcium d Glucarate, which helps clear excess estrogen and chemical estrogens from the body, and a product known as Aromastat, which contains a blend of herbal ingredients that work together to help keep your natural hormones balanced.  Aromastat contains chamomile (apigenin), chrystin, daidzein, genistein, indole-3-carbinol, and glycitein (it does contain soy isolates, so if avoiding, look for these ingredients individually, although in the case of genistein, I prefer you eat organic whole soy). For more information on natural alternatives to tamoxifen and aromatase inhibitors, please read my previous posts on the subject or visit my Shop page.

This information is for educational and thought-provoking purposes only and is not a recommendation to forgo medical advice and treatment.  This post is not intended to treat, cure, prevent, or diagnose any disease or condition. The information provided is from my research and not to be taken as scientific evidence.

In your good health,

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a holistic cancer strategist and speaker specializing in the prevention and treatment of cancer. She is a Contributing Editor for The Truth About Cancer and is on the Medical Advisory Board for BeatCancer.Org and the Advisory Board to the Radical Remission Project. Elyn has written for numerous journals and publications. She was the former Executive Director of the Emerald Heart Cancer Foundation and the creator and host of the Survive and Live Well Radio Show. To contact Elyn, visit www.elynjacobs.com. Elyn offers consults via Skype, phone, or in-person. Elyn does not provide online advice.

References:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535874/#B135-ijms-18-01381

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535874/

https://www.ncbi.nlm.nih.gov/pubmed/28396216

https://www.hindawi.com/journals/jdr/2015/916585/

https://www.ncbi.nlm.nih.gov/pubmed/30487265

https://diabetes.diabetesjournals.org/content/68/2/291

DISCLAIMER:
Elyn Jacobs does not provide medical advice. The information provided is for general information only. No online site should be used as a substitute for personal medical attention.

This information is for educational purposes only and is not a recommendation to forgo medical advice and treatment.  This post is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist. The information provided is from my research and not to be taken as scientific evidence.

Affiliate Links Disclosure:

Some product links on some posts are affiliate links. This website is monetized in part through the use of affiliate links. This means that if you were to click on a link that is an affiliate link and purchase an item after clicking on that link, I may receive a small percentage of the sales price. I only recommend products that I love and use often. Thank you for your support!

Follow Elyn on Facebook

Follow Elyn on LinkedIn

 

 

What You Need to Know About Sugar and Breast Cancer—It’s NOT What You Think!

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Alternatives to Anti-Hormone Therapy For Breast Cancer, Alternatives to Tamoxifen, Anticancer foods, foods for colon cancer, foods for breast cancer, aromatase inhibitors, Boosting Estrogen, Breast Cancer, Cancer, Estrogen and Breast Cancer, Hormone Balance, SERMS, Tamoxifen, Uncategorized on October 20, 2019 at 7:00 pm

Cancer loves sugar, we all know that – sugar feeds cancer and suppresses the immune system. The effects of each dose can last for 5-6 hours. The more sugar we eat, the faster cancer cells can grow. But do you know why sugar happens to love breast cancer?

Cells require sugar for energy, but it needs help to get into the cells. Insulin is the helper that attaches to and signals cells to absorb sugar from the bloodstream. Food sources that boost insulin production and regulate blood sugar levels include red cabbage, sweet potatoes, fenugreek seeds, curcumin, blueberries, vitamin D, and Ceylon cinnamon (so please continue to eat them). However, consuming sugar (sweets, pasta, and many bread, including whole wheat) raises blood sugar levels quickly. The pancreas responds to this by pumping out insulin to lower blood sugar levels. Over time, this can lead to decreased insulin sensitivity. When this happens, the body begins to ignore the signal to take glucose out of the bloodstream and put it into our cells. This triggers the body to start producing even more insulin. The more insulin, the more circulating estrogen there is to stimulate breast cancer cells.

     Sugar spikes insulin levels. Insulin regulates how much estrogen is available to stimulate breast cells. The more sugar you consume, the higher your circulating estrogen levels.

In the Fall 2019 issue of Breast Cancer Wellness there is an excellent article on sugar and its connection to estrogen, written by Dr Christine Horner, M.D. According to Horner, sugar “attacks a portion of the estrogen cycle, making more estrogen available to attach to the estrogen receptors in breast tissue. Insulin regulates how much of the estrogen in your blood is available to attach to estrogen receptors in your breast tissue. When estrogen travels in the blood, it either travels alone seeking a mate (an estrogen receptor), or it travels with a partner (a protein binder) that prevents it from attaching to an estrogen receptor. Insulin regulates the number of protein binders in the blood. So, the higher your insulin levels are, the fewer the number of protein binders there will be and therefore the more free estrogen that will be available to attach to estrogen receptors.  In other words, when your insulin levels are up, free-estrogen levels are up too. And both of them speed up cell division. That’s why high insulin levels increase your risk of breast cancer so much.” She further explains that “when insulin attaches to its receptor, it has the same effect as when estrogen attaches to its receptor; it causes cells to start dividing. The higher your insulin levels are, the faster your breast cells will divide; the faster they divide, the higher your risk of breast cancer is and the faster any existing cancer cells will grow.”

Addressing Estrogen Receptors with SERMS

To address estrogen receptor positive cancers, oncologists often recommend SERMS (selective receptor modulators) such as tamoxifen. However, tamoxifen is a carcinogenic drug that comes with significant side effects, including an increased risk of cancer.

Research shows that phytoestrogens,  plant-derived estrogens that can actually cause anti-estrogenic effects by binding to estrogen receptors (much like tamoxifen), might be worthy of consideration. The potential effects of dietary phytoestrogens have been studied to lower the risk of menopausal symptoms, cardiovascular disease, obesity, metabolic syndrome and type 2 diabetes, brain function disorders, and cancers of the breast, ovaries, endometrium, prostate, and other cancers

I will address the role of phytoestrogens as holistic selective estrogen receptor modulators (SERMS vs Tamoxifen) in a subsequent post.  I will also address the question of ‘do aromatase inhibitors actually increase your risk of breast or other cancers?’. Meanwhile, you may wish to read my many articles on natural alternatives to anti-hormone therapies such as aromatase inhibitors and tamoxifen.

In your good health,

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a holistic cancer strategist and speaker specializing in the prevention and treatment of cancer. She is a Contributing Editor for The Truth About Cancer and is on the Medical Advisory Board for BeatCancer.Org and the Advisory Board to the Radical Remission Project. Elyn has written for numerous journals and publications. She was the former Executive Director of the Emerald Heart Cancer Foundation and the creator and host of the Survive and Live Well Radio Show. To contact Elyn, visit www.elynjacobs.com. Elyn offers consults via Skype, phone, or in-person. Elyn does not provide online advice.

DISCLAIMER:
Elyn Jacobs does not provide medical advice. The information provided is for general information only. No online site should be used as a substitute for personal medical attention.

This information is for educational purposes only and is not a recommendation to forgo medical advice and treatment.  This post is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist. The information provided is from my research and not to be taken as scientific evidence.

Affiliate Links Disclosure:

Some product links on some posts are affiliate links. This website is monetized in part through the use of affiliate links. This means that if you were to click on a link that is an affiliate link and purchase an item after clicking on that link, I may receive a small percentage of the sales price. I only recommend products that I love and use often. Thank you for your support!

Follow Elyn on Facebook

Follow Elyn on LinkedIn

[i] https://www.sciencedaily.com/releases/2019/02/190212162216.htm

 

Gluten-Free Anticancer, Anti-inflammatory Seeded Flatbread

In Alternatives to Anti-Hormone Therapy For Breast Cancer, Anticancer foods, foods for colon cancer, foods for breast cancer, Breast Cancer, Estrogen and Breast Cancer, Hot Flashes and Night Sweats, Tamoxifen, Uncategorized on January 21, 2019 at 8:51 am

This protein-rich, anticancer, anti-inflammatory flatbread is delicious with runny eggs (and lots of cancer-fighting herbs) or as a canvas for sliced avocado and tomato or other open-faced sandwich offerings. I also love it with pesto and finely grated Parmesan cheese when the bread is hot from the oven.

flatbread

Buckwheat is actually not wheat, but rather a seed that is naturally gluten-free. It is rich in protein, vitamins, and minerals. Buckwheat has been found to boost heart health and reduce blood sugar and cancer risk. Its antioxidants, flavonoids, and other compounds fight free radicals and reduce inflammation.

Flax and sesame seeds offer anti-cancer lignans which can significantly reduce tumor growth by increasing cell death and decreasing angiogenesis (the growth of new blood vessels that allow cancer to advance). Lignans are phytoestrogens that can relieve the symptoms of menopause and modulate the effects of estrogen in the body by connecting to their receptors (just as tamoxifen does) thus inhibiting cancer cell replication. This is because they have a very similar chemical structure as to an estrogen molecule. Studies have found that consuming 25-30 grams of flaxseed daily inhibits the growth of ER+ and ER- breast cancers and reduces the metastasis of breast tumors.[[i] Flaxseed is also high in omega 3’s, alpha-linolenic acid (ALA), and antioxidants which further defeat cancer.

While flaxseeds have approximately 100 times more lignans than other foods, a new study showed that sesame seeds may rival flax in the lignan arena.[ii]  The researchers found sesame to be a better inducer of programmed cell death (apoptosis) in breast cancer cells than flaxseed. It could be that whole sesame seeds are more easily digested than whole flax and that particular study used un-ground flaxseed[iii], so more research needs to be done (I always recommend grinding flax just prior to ingestion). Meanwhile sesame seeds are a rich source of plant-based calcium and protein, and certainly a good source of lignans. They also help lower blood pressure and oxidative stress, and reduce diabetic neuropathic pain and inflammation.

Chia seeds are anti-inflammatory and high in protein and omega 3′ fatty acids. Poppy seeds offer vitamins and minerals, and bestow antioxidant and anti-inflammatory activities that support the blood, bones, and gut.

Ingredients:

  • ¾ cup rolled oats
  • ½ cup buckwheat groats
  • 2 Tbs. flax seeds
  • ¼ cup raw, sprouted sunflower seeds
  • 1 Tbs. chia seeds
  • 1 ½ tsp. dried oregano
  • ½ tsp. dried parsley
  • ½ tsp. dried thyme
  • ¼ tsp. baking powder
  • ¼ tsp. garlic powder
  • ¼ tsp. fine grain sea salt
  • 1 cup unsweetened coconut milk
  • 1 Tbs. pure maple syrup
  • 1 Tbs olive or coconut oil (melted)
  • Seed topping (recipe below)
  • Olive oil, for drizzling (optional)

 Instructions:

  1. Preheat the oven to 350 degrees F. Line a small rimmed 10 x 13 inch pan with parchment paper
  2. In a spice or coffee grinder, grind the oats until they resemble flour; transfer to a medium bowl and do the same with the groats. Coarsely grind the flax seeds and add them to the bowl. Add the sunflower and chia seeds, the spices, baking powder, and salt. Whisk to combine.
  3. Add the coconut milk, syrup, and oil and stir until combined. Spread the batter onto the prepared baking sheet.  It will not leak, but keep it on the paper. Sprinkle it with the seed mixture and coarse Celtic sea salt to taste. Drizzle with a very small amount of olive oil, if desired.
  4. Bake 20 minutes on a low rack in the oven. Move the pan to the upper rack and rotate the pan; bake 5-10 minutes more or until firm to the touch.
  5. Allow to cool in the pan on a cooling rack for 15 minutes. Slide the parchment to a board and cut into 6-8 pieces with a pizza cutter or sharp knife.
  6. Store the flatbread in an airtight container for a few days or freeze to enjoy later.

Seed Topping:

2 Tbs. raw, sprouted sunflower seeds

½ tsp. chia seeds

2 tsp. poppy seeds

2 Tbs. sesame seeds

This recipe was inspired by a recipe in Angela Liddon’s amazing “The Oh She Glows Cookbook”. There are so many delicious recipes in this book –mouthwatering soups, stews, and more so I highly recommend it.

[i] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808339/

[ii] http://www.greenmedinfo.com/blog/sesame-may-eclipse-flaxseed-ultimate-healing-seed?fbclid=IwAR2YKTl7BTIY2teL4IhXo0EJ6ylpl4pM2y5FPppBpC1Gi4oEeU7j1a7tZTg

[iii] https://www.ncbi.nlm.nih.gov/pubmed/22136581

You can find groats and sprouted seeds at Whole Foods and other markets or here at Amazon:               Buckwheat Groats         Raw, Sprouted Sunflower Seeds

Enjoy in good health,

Elyn

Elyn Jacobs is a holistic cancer strategist and speaker specializing in the prevention and treatment of cancer. She is a Contributing Editor for The Truth About Cancer and is on the Medical Advisory Board for BeatCancer.Org and the Advisory Board to the Radical Remission Project. Elyn has written for numerous journals and publications. She was the former Executive Director of the Emerald Heart Cancer Foundation. To contact Elyn, visit www.elynjacobs.com. Elyn offers consults via Skype, phone, or in person.

This information is for educational purposes only and is not a recommendation to forgo medical advice and treatment.  This post is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist. The information provided is from my research and not to be taken as scientific evidence.

Affiliate Links Disclosure:

Some product links on some posts are affiliate links. This website is monetized in part through the use of affiliate links. This means that if you were to click on a link that is an affiliate link, and purchase an item after clicking on that link, I may receive a small percentage of the sales price. I only recommend products that I love and use often. Thank you for your support!

Follow Elyn on Facebook

Follow Elyn on LinkedIn