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Archive for the ‘colon cancer’ Category

Magnolia, Cancer’s Worst Enemy

In Alternative Cancer Therapies, Breast Cancer, Cancer, colon cancer, Uncategorized on December 8, 2017 at 7:43 am

While many people have taken magnolia to reduce stress-related symptoms such as anxiety, insomnia, and depression, the health benefits of magnolia go well beyond that. Importantly, magnolia can be used to help detoxify the body, soothe the digestive system, and to help prevent and treat cancer.

The hearty nature of magnolia shrubs and trees on which the beautiful magnolia flower grows has allowed them to offer a powerful organic nutrient with amazing health benefits. These virtues are recognized by modern medicine, Chinese Traditional medicine, and herbalists worldwide.  This bioactive natural product is known as honokiol.

Recent studies have demonstrated anti-inflammatory, anti-angiogenic, apoptotic, anti-oxidative, and overall anti-cancer properties of honokiol in vitro and in preclinical models. Honokiol targets multiple signaling pathways including nuclear factor kappa B (NF-κB) signal transducers and activator of transcription 3 (STAT3), epidermal growth factor receptor (EGFR), and mammalian target of rapamycin (m-TOR), which have great relevance during cancer initiation and progression.

Honokiol also shuts down the leptin signaling network, which is significant for obese patients. Leptin-induced tumors quickly learn to evade all the usual biological checkpoints that keep tumors from growing and spreading.  Once the leptin helps the tumor achieve this state, the tumor is poised to migrate and morph from a non-invasive tumor to an invasive tumor. Research done at Johns Hopkins found that honokiol is able to suppress some of the proteins in the leptin network.

The link between obesity, leptin, and breast cancer is well known, yet this hasn’t changed how breast cancer patients are diagnosed or treated, nor do doctors check patients for leptin or leptin receptor levels. Some studies suggest that breast cancer cells that have been exposed to high levels of leptin over several years might also be less sensitive to the chemo drug tamoxifen, rendering it, well,  less effective (just one more reason why traditional remedies are not always the best solution).

Hopefully more doctors will discover this natural remedy soon, but in the meantime, you are empowered to take advantage of magnolia’s offerings. The immense chemo-preventive (anticancer) capabilities of magnolia cannot be overlooked.

Anticancer Benefits of Magnolia:

  • stimulates the lymphatic system and increases the level of toxins being eliminated from the body
  • inhibits angiogenesis (the development of new blood vessels tumors require to survive)
  • powerful antioxidant
  • promotes apoptosis (cancer cell death)
  • down-regulates cancer-promoting genes
  • inhibits the growth of Helicobacter pylori, known to significantly increase the risk for gastric cancers
  • able to cross the blood-brain-barrier and inhibit brain tumor growth[i]
  • increases sensitivity to radiation -induced cytotoxicity in lung and other cancers
  • shuts down the leptin signaling network

While studies have found honokiol to be effective in gastrointestinal, breast, head and neck, prostate, ovarian, lung, skin, brain, and many other cancers, here are just a few specifics of this powerful magnolia:[ii]

  • inhibits the growth in breast cancer cell lines (MDA-MB-231, SK-BR-3, MDA-MB-436, ZR-75-1and T47-D, MCF-7, 4T1) in a dose dependent manner regardless of their HR, HER2 or p53 status
  • is effective against estrogen-receptor positive as well as estrogen-receptor negative breast cancers
  • induces apoptosis in human prostate cancer cells irrespective of their androgen responsiveness or p53 status, and significantly decreases PSA counts
  • exhibits growth-inhibitory effects against two human pancreatic cancer cell lines (MiaPaCa and Panc1)
  • effective in leukemia cell lines viz. B-CLL and Molt 4B
  • induces apoptosis in human multiple myeloma cell lines including dexamethasone-sensitive (MM.1S) and dexamethasone-resistant (MM.1R, RPMI-8226, U266 and SU-DHL-4) cells and in tumor cells
  • significantly inhibits the invasion and colony formation of highly metastatic renal cell cancers cells 786-0 in a dose-dependent manner[iii]

How to Take Magnolia:

The bark, cones and leaves of the magnolia tree can be cooked and boiled down to a syrupy extract. Given that many of us do not have a field of magnolia in our back yards, a supplement may be best.

Small doses (30 mg) may be effective for anxiety and depression.  Slightly more might be helpful for those dealing with intense stress or insomnia. My oncologist used to call it “herbal Valium—all the relief without the wobbly knees”. He recommended it for sleep and stress relief as well as for cancer. The brand I take, NutriCology comes in capsule form, 200mg. The suggested dose is one daily, before bed. For smaller doses, you can buy it in powder formHonoPure is another excellent product that comes highly recommended.

The suggested dosage for cancer averages between 200 and 800 mg, up to three times a day (but limit to one dose before bed if drowsiness will be an issue and high doses only under the guidance of a medical doctor).

Magnolia should not be taken by pregnant women or at very high doses as it may cause headaches, dizziness, and vertigo. Keep magnolia away from infants and animals. Magnolia may cause a sedative effect and can interact with alcohol. Operating dangerous equipment or driving while taking magnolia extract is not recommended. For best results, take before bed.

This information is for educational purposes only and is not intended to treat, cure, prevent, or diagnose any disease or condition. This post does not represent medical advice nor should it be considered to be medical advice or a replacement for medical advice.  I encourage you to discuss this information with your integrative oncologist, naturopathic doctor, or conventional oncologist and make your own decisions.  The information provided is from my research and not to be taken as scientific evidence. 

As an Amazon Affiliate, we may earn a small commission for the sale of products purchased from this site. These small commissions help to pay for the maintenance of this site as well as for the time spent researching and writing on topics relevant to your optimal health, but are achieved at no additional cost to  you.

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a breast cancer survivor and certified holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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REFERENCES:

https://www.realnatural.org/magnolia-bark-extract-treats-multiple-invasive-cancers/

https://www.sciencedaily.com/releases/2008/07/080711214125.htm

 

https://www.spandidos-publications.com/ijo/46/6/2293

https://hub.jhu.edu/2016/07/06/magnolia-honokiol-breast-cancer-obesity/

[i] /www.ncbi.nlm.nih.gov/pmc/articles/PMC3663139/

[ii] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663139/

[iii] https://www.spandidos-publications.com/ijo/46/6/2293

Broccoli and Leaky Gut: Who Knew

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Anticancer foods, foods for colon cancer, foods for breast cancer, Breast Cancer, Cancer, colon cancer on October 30, 2017 at 4:19 pm

broccoli sprouts aIt is no revelation that cruciferous vegetables such as broccoli fight cancer in many ways.  Notably, broccoli contains a high amount of the cancer-busting and immune boosting substance sulforaphane. New research, however, shows that broccoli –and its cousins– actually heal leaky gut as well.

Leaky gut, or gut permeability, has risen to the forefront of medical concern as it has been found to be a source of many maladies, including cancer. This is because leaky gut blocks nutrient absorption and allows toxins from ingested foods to enter the blood stream. Dr Max Gerson had concern for this years ago, citing insufficient nutrition and overwhelming environmental toxicity to be the root cause of many dis-ease. Good gut-barrier function helps protect the intestines from toxins while allowing nutrients to be absorbed.

“There are a lot of reasons we want to explore helping with gastrointestinal health and one reason is if you have problems, like a leaky gut, and start to suffer inflammation, that may then lead to other conditions, like arthritis and heart disease,” said Perdew. “Keeping your gut healthy and making sure you have good barrier functions so you’re not getting this leaky effect would be really big.” Gary Perdew, the John T. and Paige S. Smith Professor in Agricultural Sciences, Penn State.

Recent research shows that gut health affects overall health, including systemic inflammation, heart disease, and cancer. Broccoli, and other cruciferous vegetables, appears to offer assistance.

AHR (Aryl hydrocarbon receptor) is found in many organs. It binds environmental toxins, detoxifying the carcinogenic effects. Cruciferous vegetables contain an organic chemical compound called indole glucosinolates, which breaks down in the stomach into substances known as indolocarbazole (ICZ).

In a recent study performed at Penn State University, it was found that ICZ  activates AHR. In doing so, it  boosts immune function and improves the balance of the microbiome in the human gut, enhancing host barrier function.[i]

How much do you need?  Well, a lot —  and every day.  Consider a good fist-full of broccoli sprouts, a cup of Brussels sprouts, or about 3 and half cups of broccoli per day (note that when sliced, you will yield more per cup of Brussels or broccoli, so you will need less).

Just remember that it is important to avoid things that irritate the gut lining; otherwise, it could be an uphill battle. Avoid alcohol, caffeine, coffee, chocolate, chemicals in foods, gluten, processed foods, antibiotics, NSAIDs,  as well as vinegar and other fermented foods (for some people).  Candida also contributes to leaky gut. Some people may also need to avoid grains. This is because grains can be difficult for the body to breakdown and digest, resulting in inflammation in the digestive tract.

 

So, What’s the Big Deal About Sulforaphane?

Sulforaphane, abundant in broccoli, is a sulfur-containing compound found in cruciferous vegetables. It supports matrix metalloproteinase-9 (MMP-9) activity which reduces the breakdown of connective tissue within a cell that impede the expansion of existing tumors. Matrix MMP-9 plays important roles in tumor invasion and angiogenesis. Secretion of MMP-9 has been reported in various cancer types including lung, colon, and breast cancer.

Sulforaphane also kills off cancer cells, including cancer stem cells, which is essential for combating cancer metastases. It also restrains certain pro-inflammatory compounds that are associated with chronic inflammation and cancer.

Sulforaphane also helps support the anti-inflammatory Nrf2 pathway which protects cells against oxidative and free radical activity. It supports the detoxification process by inducing Phase 2 detoxification enzymes, inhibiting the activation of pro-carcinogens, and by boosting cellular glutathione levels.  Sulforaphane promotes cancer cell death and inhibits cancer cell proliferation. It also supports the immune system and in particular, increases Natural Killer Cell activity.

This is just one more reason to enjoy cruciferous vegetables daily.  Cauliflower, watercress, kholrabi, and arugula are a few of the other amazing crucifers aside from broccoli.kholrabi

Just remember to lightly steam or cook crucifers.  Adding some organic grass-fed (pastured) butter or olive oil can help as well.  Avoid overcooking as this will destroy the health benefits.  If you prefer your veges to be, well, a bit more well-done, then chop them and allow to sit for 40 minutes before cooking. This allows the family of enzymes known as myrosinase to form. Myrosinase converts glucoraphanin to sulforaphane.  Without myrosinase, the body cannot absorb surlforaphane. It also helps to consume myrosinase-containing foods, such as mustard seed, with cruciferous veges as this will further maximize sulforphane availability.

A tasty side dish could include lightly cooked broccoli dressed with lemon-infused olive oil, black pepper, and some mustard seeds or powder. Freshness counts, so when possible, shop your local farmer’s market and cook your produce the same day (much of the value is lost after 5 days or so).

Curcera-SGS is an excellent supplement if you cannot find broccoli sprouts.

For more information on the benefits of cruciferous vegetables, please read my post Broccoli and Watercress Sprouts Fight Cancer.

Another good read is Eat Dirt: Why Leaky Gut May Be the Root Cause of Your Health Problems and 5 Surprising Steps to Cure It.

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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[i] http://news.psu.edu/story/486322/2017/10/13/research/it-or-not-broccoli-may-be-good-gut

Health Benefits of Aronia Berries

In Alternative Cancer Therapies, Anticancer foods, foods for colon cancer, foods for breast cancer, Breast Cancer, colon cancer, Uncategorized on July 11, 2017 at 1:36 pm

Aronia berries, also known as chokeberries, have numerous healing abilities. Notably, they have a higher concentration of antioxidants than any other fruit, beating out cranberries, blueberries, strawberries, pomegranate, and others. Antioxidants protect your cells from the damaging effects of oxidation, boosting health and helping to protect against cancer. Certain agents in aronia, such as caffeic acid, cyanidin-3-galactoside, delphinidin, epicatechin, and malvidin have been studied for their health-promoting properties.  Combined, these agents are anti-bacterial, anti-viral, and antidiabetic. But, there is so much more to these dark pigmented berries.

Here are just some of the amazing health benefits of aronia Berries:

  • Promote good urinary tract health, which means less urinary tract infections (UTIs);
  • Lower cardiovascular risk as they improve blood circulation and make blood vessels stronger. They improve elasticity of blood vessels and prevent their clogging, fight the formation of arterial plaque, and lower cholesterol;
  • Help balance blood pressure;
  • Help prevent and treat diabetes as they have been found to lower blood sugar levels and improve the body’s own natural production of insulin;
  • Help with gut issues, including gastric ulcers and diarrhea
  • Help reduce weight and body fat;
  • And, last but not least, aronia berries are anti-cancer.

Several of the compounds in aronia are natural cancer fighters, especially against cancer of the breast, bladder, stomach, colon, lungs, ovaries, and skin. One study even found that when paired with curcumin, aronia could kill brain cancer cells. Researchers have found that these amazing berries slow the growth of cancer cells. Some studies also show that not only was growth slowed, but cancer cells were killed.[i]

The phenols in aronia berries (particularly proanthocyanins and anthocyanins) also disinfect the bloodstream and remove toxic substances from the body. Aronia has been found to help with herpes, and thus could be effective against the Epstein Barr Virus (EBV) as well. EBV is known to be connected to the development of various cancers.

In one study, Caco-2 colon cells exposed to chokeberry resulted in a dramatic reduction in proliferation (30-40%) and viability was inhibited by around 20%.  A positive change in gene expression was also noted. The genes that changed were found to be ones related to cell proliferation, tumor migration, and colon carcinogenesis. [ii] Another study also found that aronia can up-regulate tumor suppressor genes for colon cancer.[iii]

Unfortunately, aronia berries do not taste very good.  They are sour and taste a bit like cranberries. But, the good news is that aronia is naturally pest-resistant and therefore, does not require the use of agricultural toxins.  What that means to you is you may not need to worry about unhealthy chemicals in the fruit. The berries themselves are more powerful than just the juice, so it is best to choose fresh or dried berries if you can find them. You can buy them in powder and supplement form as well.

Elyn

~~If you don’t know your options, you don’t have any~~

ej portrait 150resElyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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[i] http://news.bbc.co.uk/2/hi/health/6954696.stm

[ii] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2474921/

[iii] https://www.ncbi.nlm.nih.gov/pubmed?term=16860979

 

 

What You Need to Know About the Status of Intravenous Vitamin C

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Anticancer foods, foods for colon cancer, foods for breast cancer, Breast Cancer, Cancer, cancer stem cells and recurrence, chemo and cancer stem cells, colon cancer, foods that target cancer stem cells, Healing Cancer Naturally, High Dose Vitamin C and Cancer, IVC and Cancer, what causes cancer stem cells, what causes cancer to spread on June 26, 2017 at 4:40 pm

Some people seem to be under the impression that it will soon be impossible to get intravenous vitamin C. There is no cause for alarm! While the FDA has been quietly attempting to ban this vital cancer treatment, it is still widely available.

About three years ago, the FDA created a shortage of IV bags, which did raise the price of the treatment by a few dollars. They also banned one manufacturer from making the injectable vitamin C solution. There is no doubt the FDA is up to no good, and we may see higher prices coming our way because of this. Clearly this is a ploy put in motion by Big Pharma with the blessings of the FDA.

However, many compounding pharmacies are still offering it, and none of the doctors I know of are having difficulties with supply.

Instead of banning IVC, the government should be grateful for this therapy.  But alas, a non-patentable solution would not line the pockets of Big Pharma, and sadly, those pockets are apparently more important than our lives.

High Dose Vitamin C a Valuable Cancer Treatment

In the past 46 years, trillions of dollars have been spent on cancer research and treatment since Nixon declared the ‘war on cancer’ in 1971.   The war was lost. The money was spent; the patients suffered; the patients died.

This is because cancer patients do not die from primary tumors.  We know that metastases are what kills 90% of cancer patients. Cancer stem cells (CSCs) are suspected to be the cause of almost if not all of the metastases.

Yet, most oncologists focus on the primary tumor as if eradicating it will save the patient. They even recommend radiation to get rid of the pesky cells in a breast, for example. They offer chemotherapy to chase down lingering cancer cells.

But cancer stem cells are not eliminated by radiation or chemotherapy, and worse, these treatments can actually make them stronger.  Vitamin C has been found to kill cancer cells and do no harm to the patient –and it does not empower CSCs.  AND, unlike chemotherapy and radiation, we now know that it has the potential to kill the stem cells.

Oral High Dose Vitamin C Kills Cancer Stem Cells

Vitamin C has long been thought to be an effective addition to cancer protocols.  New research has found that oral high dose vitamin C given in conjunction with the common antibiotic doxycycline can kill cancer stem cells.[i]  Doxycycline kills cancer stem cells by suppressing the production of key DNA proteins driving these cells from oxygen to sugar metabolism (the process of glycolysis). In cancer cells, high-dose vitamin C treatment induces cell death by inhibiting glycolysis and thus interrupting the cell’s food supply (energy).  Plus, while doxycycline kills many cancer cells, others become resistant. The study found resistant cells were then destroyed by oral vitamin C. According to the researchers, the oral dose needed would be 3000 mg of C, taken four times daily.

Importantly, for those of you who, like me, prefer not to take pharmaceuticals, natural compounds such as oils extracted from oregano and thyme mimic doxycycline, and have been found to be just as effective. [ii]

For more information on utilizing high dose vitamin C, please read High Dose Vitamin C: The Other Cancer Therapy.

However, it is important to know that in high doses, oral vitamin C is just as effective (or possibly even more so) than Intravenous Vitamin C (IVC). This is important as IVC can be very expensive. You can consume high levels of oral C without the typical bowel intolerance by using Liposomal C or  Sodium Ascorbate. My two favorite brands of liposomal C are Mercola  and  Lypo-Spheric .  You can also make it at home.  One trip to google will provide DIY methods.

For more on CSC’s please view Cancer Stem Cells– Could They Be the Key to Metastasis?

ej portrait 150resElyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website, www.elynjacobs.com. Elyn offers consults via Skype, phone or in person.

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Resources and information:

http://www.anh-usa.org/action-alert-now-the-fda-is-going-after-vitamin-c/

https://elynjacobs.com/2016/09/17/high-dose-vitamin-c-the-other-cancer-therapy/

[i] https://www.lewrockwell.com/2017/06/bill-sardi/starving-cancer-cells-existence/

[ii] http://www.journalofdairyscience.org/article/S0022-0302(16)30897-9/fulltext

http://www.sciencedirect.com/science/article/pii/S0378517315303884

What You Need to Know About Mutations in the p53 Cancer Tumor Suppressor Gene

In Alternative Cancer Therapies, Alternatives Cancer Treatment, Anticancer foods, foods for colon cancer, foods for breast cancer, colon cancer, High Dose Vitamin C and Cancer, Radiation on January 3, 2017 at 2:34 pm

The word mutation just doesn’t sound like something good. By definition, a mutation is a permanent change in DNA. Mutations, for the most part, are harmless except when they lead to tumor formation. 

Likely you have heard about BRCA mutations. BRCA genes are tumor suppressor genes. BRCA mutations can increase one’s risk for cancers of the breast and ovaries. However, these mutations are only responsible for about 5-10% of all breast cancers and about 15% of ovarian cancers. But, the little-known p53 mutation affects far more people. About 50% of all cancers have a mutated p53 gene.

What is P53?
The p53 protein is located in the nucleus of cells throughout the body, where it attaches (binds) directly to DNA. (It is actually the TP53 gene that provides instructions for making the tumor protein p53 but for simplicity, I will say p53.) P53 regulates cell division by keeping cells from growing and dividing too fast or in an uncontrolled way.

P53 plays a critical role in determining whether damaged DNA will be repaired or a damaged cell will self-destruct (undergo apoptosis). If the DNA can be repaired, p53 activates other genes to fix the damage. If the DNA cannot be repaired, this protein prevents the cell from dividing and signals it to undergo apoptosis. By stopping cells with mutated or damaged DNA from dividing, p53 helps prevent the development of tumors.

Mutated P53
P53 mutations lead to a version of p53 that cannot regulate cell growth and division effectively. Specifically, the altered protein is unable to trigger apoptosis in cells with mutated or damaged DNA.

DNA can be damaged by agents such as toxic chemicals, radiation such as gamma rays, X-rays — even UV light can interact with compounds in the cell generating free radicals which cause chemical damage to DNA.

Since all cells in our body contain DNA, there are lots of places for mutations such as p53 to occur. When p53 does not operate properly, damaged DNA can replicate, producing mutations and DNA rearrangements that contribute to the development of a highly transformed, metastatic cell. Many cancer cells inactivate p53, allowing the cells to evade death and continue proliferating up to becoming a tumor.

Mutant p53 proteins not only lose their tumor suppressive activities but often escalate the development of cancerous tumors by providing them with growth and survival mechanisms. Interestingly, mutations in the p53 gene have been shown to occur at different phases of the cancer process, contributing to tumor initiation, promotion, aggressiveness, and metastasis.

P53 mutations contribute to risk of brain tumors and breast, prostate, colon and other cancers. Mutations in p53 gene usually correlate with poor outcome and early recurrence in cancer.

Enough of the bad news.

The Good News
What is really exciting is that this repair gene, p53, which protects cells from becoming cancerous, can be highly activated by many natural substances—substances that do not have the negative side effects of drug therapies. The ability to activate p53 within cells may halt cell proliferation, or even cause cancer cell death.

 

watercressFor example, cruciferous vegetables (especially watercress with its high content of PEITC) have been found to support p53. PEITC (phenethylisothyanate) decreases the levels of mutated p53 and helps to restore the normal activity of this protein. Vitamin C is another promoter of P53, which is one of the reasons intravenous Vitamin C (IVC) and high-dose oral C therapies are so effective against cancer.
The resveratrol in red grapes and red wine (organic please, and research shows dark, red wines are best) also activates the P53 gene. IP6 has been shown to alter the expression of p53. Zinc helps protect the p53 gene against cancer-forming mutations. Selenium can activate p53 in response to genetic damage, helping the cell to repair its DNA. Herbs such as sage, rosemary, ginger, curcumin, and ashwaganda support p53. Thymoquinone extracted from black seed triggers apoptotic cell death in colorectal and other cancers cells via the p53- dependent mechanism. Anthocyanins, abundant in red  onions, inhibit the damage that impaired p53 can cause on cells and tissue. Anthocyanins are also found in blackberries, blueberries, purple grapes, eggplant, and avocado.

P53 Supporters:
• Cruciferous vegetables, especially watercress
IP6
Resveratrol
• Herbs such as sage, rosemary, ginger, curcumin, and ashwaganda
• EFA’s from omega 3 fatty acids (please use caution with fish oil supplements as they can be toxic). For a plant based formula, you could take BodyBio Balance Oil.
• Licorice
• Mistletoe
Vitamin D
Selenium
• Vitamin C
Zinc
Black Seed
Clinoptilolite (a special form of Zeolite)
On the other hand, processed foods, refined flours, and sugars will impair P53. Smokey flavoring and smoked foods can also damage DNA. Chemicals such as benzene and perchloroethylene, two volatile organic compounds, negatively affect p53, possibly causing them to stimulate rather than suppress cell proliferation.

The late Integrative Oncologist Dr Mitchell Gaynor, MD was famous for his passion for explaining that we can change the way our genes behave by making good dietary choices. For more gene-changing foods and lifestyle habits read Dr. Gaynor’s book, The Gene Therapy Plan, Taking Control of Your Genetic Destiny with Diet and Lifestyle.

P53 and BRCA are not the only genetic mutations that increase cancer risk. For example, mutations in th e CHEK2 gene are associated with an increased risk of developing many types of cancer, including breast, colon, prostate, and other cancers — sometimes at young ages. If you have a history of hereditary cancer you might benefit from genetic testing for CHEK2 and others.

Testing
You can request to be tested for the p53 mutation. The test is called the p53 Gene Mutation Analysis, Cell Based, offered by labs such as Quest Diagnostics. If your insurance company does not accept Quest or another lab that offers this test, you can petition your carrier for a Network Gap Exception.
You may need to consult a genetic counselor if your oncologist does not routinely check for mutations as these tests are not part of your typical pathology report.

Found this article helpful?  Please let me know.

 

Elyn

~~If you don’t know your options, you don’t have any~~

Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. Elyn is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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http://www.ambrygen.com/tests/chek2-related-cancer
http://www.nbs.csudh.edu/chemistry/faculty/nsturm/CHEMXL153/DNAMutationRepair.htm
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827900/
https://ghr.nlm.nih.gov/gene/TP53
https://www.ncbi.nlm.nih.gov/pubmed/14608114
http://www.ambrygen.com/tests/chek2-related-cancer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135636/

Vibrant Exotic Anti-Cancer Gems

In Breast Cancer, Cancer, colon cancer on December 2, 2016 at 5:21 pm

When we talk about an anticancer diet, color is important.  If you have never tried dragon fruit or watermelon radishes you are in for a delectable  and beautiful surprise.   Both are powerful anticancer gems that you will want to see on your plate time and again.

 

dragon-4Dragon Fruit.  While we are all enjoying fall produce, many of us are clamoring for juicy fruit and vibrant colors on our plates.  Given that melons and berries are not abundant locally, nor tasty right now, I ventured to try something different–dragon fruit.  Granted this comes a long way to our table, but I figured what the heck—most fruit does this time of year so why not try something new.

Dragon fruit is an exotic and delicious fruit that is of the cactus family.  It hails from Mexico, South America, and Central America, as well as Thailand and Vietnam.dragon-2

If you have never tried or even heard of it, know that it is eye-catching and is loaded with power-nutrients.  The taste is a cross between kiwi and watermelon, with kiwi-like seeds. The variety I purchased was beet-red and stunning.

Dragon Fruit (also known as pitayas), is excellent for immune system health.  It’s high levels of vitamin C stimulate the activity of other antioxidants as they seek out and eliminate free radicals—which are linked to the development of cancer.

The seeds in dragon fruit are also high in omega 3 and 6 fatty acids that can help reduce triglycerides and cardio issues.  Compounds in dragon fruit can also help with the removal of toxic heavy metals and protect eyesight.  Dragon fruit is high in lycopene, which can lower the risk of prostate and other cancers.  In particular, studies have shown that compounds in dragon fruit inhibit CP450 forms, which are key enzymes in cancer formation.

Dragon fruit is also loaded with B vitamins, specifically, B2, B3 and B3, so it supports health blood pressure, skin health, cholesterol levels, and thyroid function. It also aids with digestion, facilitating smooth passage and alleviating constipation. This and the high fiber content in general can help lower your risk of colorectal cancer.

Wash the outer skin, cut into quarters and peel back the skin. Eat it sliced or in chucks, in smoothies or grilled on kebabs.

radishWatermelon Radishes

If you have never eaten a watermelon radish you are in for a wonderful delight. You can find these now at your local farmer’s market. On the outside they look a bit like a turnip.  But when sliced, you will see the vibrant watermelon-like flesh, hence the name. Milder that the average radish, they can be enjoyed so many ways.  We love them sliced and sprinkled with fine Celtic sea salt or as a ‘cracker’ for cheese or dip.

Being a member of the cruciferous family,  radishes have potent anti-cancer properties. They are an excellent source of vitamin C, offering some protection from cancer by scavenging harmful free radicals, lowering inflammation, and boosting immunity. They are rich in sulforaphane, which has been shown to be effective against cancers of the breast, colon, prostate, and many others. Studies show that sulforaphane inhibits cancer cell growth and is cyto-toxic to cancer cells.

Radishes are natural detoxifiers that help to manage environmental and natural toxins such as estrogen.  Studies have found that radishes can also help to lower blood pressure and cholesterol as well.

Radishes also contain phytochemicals like indoles which are detoxifying agents, as well as zeaxanthin, lutein, and beta carotene, which are flavonoid antioxidants. They are also good sources of folate, vitamin B-6, riboflavin, thiamin, and minerals such as iron, magnesium, copper, and calcium.

You might also want to consider purple radishes, which are even milder than watermelon radishes and are equally nutritionally beneficial.

Don’t forget to visit my Shop page for supplement advice–most of the recommendations can be found locally, but for your convenience, links to resources are provided. Supplements are essential for optimal health as well as to improve the efficacy of conventional and alternative treatments. Supplements can also help to protect the body from some of the harmful effects of conventional treatment. You will also find resources for improving sleep, EMF protection, and more. Visit my website or the articles below for natural alternatives to Tamoxifen and aromatase inhibitors should you feel such therapies are not right for you.

Elyn

~~If you don’t know your options, you don’t have any~~
Elyn Jacobs is a breast cancer survivor and holistic cancer strategist who helps people make better, healthier, non-toxic choices. She emphasizes the critical nature of addressing the root cause of cancer and not just its presenting symptoms (such as the tumor). Elyn specializes in understanding the role of estrogen in breast cancer and debunks the myths associated. She brings a plethora of knowledge to her practice and will help you think outside the box so you can incorporate every lifeline you may need for long term survival. Elyn is a Contributing Editor for The Truth About Cancer and was creator and host of the Survive and Live Well Radio Show on the Cancer Support Network. She is on the Medical Advisory Board for BeatCancer.Org and is on the Advisory Board to the Radical Remission Project. Elyn was the former Executive Director of the Emerald Heart Cancer Foundation. Contact Elyn via her website. Elyn offers consults via Skype, phone or in person.

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